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Sodium Taurocholate Induced Severe Acute Pancreatitis in C57BL/6 Mice
Published on: June 28, 2021
Serum enzyme half life can be a useful factor for follow-up management of biliary pancreatitis
Joon Hyuck Choi1, Nam Lyong Kang, Sang Don Choi
1Department of Internal Medicine, Catholic University of Daegu, Daegu 712-702, Republic of Korea.
Background And Objective:
The purpose of this study was to show that the half lives of serum amylase and lipase activities could be useful factors for follow-up management of biliary pancreatitis.
Methods:
Ten patients with initial biliary pancreatitis (IBP) and six with post-endoscopic pancreatitis (PEP) were selected from those who had undergone endoscopic surgery. Serum amylase and lipase activities were examined and the relaxation patterns were investigated continuously after the endoscopic removal of the pancreatico-biliary obstruction causing this disease.
Results:
Pancreatitis in the subjects was confirmed as a biliary type since the serum bilirubin activities decreased exponentially after removal of the obstruction. The average half lives of serum amylase and lipase were both larger in the IBP, while the average peak values were higher in the PEP.
Conclusions:
Half life can be a useful factor for follow-up management of this disease.
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