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Related Experiment Video

Updated: Jun 24, 2026

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
06:39

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants

Published on: June 13, 2021

Postpartum depression.

Teri Pearlstein1, Margaret Howard, Amy Salisbury

  • 1Department of Psychiatry and Human Behavior, The Warren Alpert Medical School of Brown University, Women and Infants Hospital, Providence, RI, USA.

American Journal of Obstetrics and Gynecology
|March 26, 2009
PubMed
Summary

Postpartum depression (PPD) affects many mothers, impacting child development. Early recognition and treatment by healthcare providers are crucial, though barriers like access to care and breastfeeding concerns persist.

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Using Chronic Social Stress to Model Postpartum Depression in Lactating Rodents
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Using Chronic Social Stress to Model Postpartum Depression in Lactating Rodents

Published on: June 10, 2013

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Last Updated: Jun 24, 2026

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
06:39

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants

Published on: June 13, 2021

Using Chronic Social Stress to Model Postpartum Depression in Lactating Rodents
07:30

Using Chronic Social Stress to Model Postpartum Depression in Lactating Rodents

Published on: June 10, 2013

Area of Science:

  • Reproductive Health
  • Maternal Mental Health
  • Child Development

Background:

  • Postpartum depression (PPD) affects up to 15% of mothers, with established negative impacts on child development.
  • Psychosocial and biological risk factors for PPD are increasingly identified.
  • PPD remains under-recognized and under-treated, highlighting a critical gap in maternal healthcare.

Purpose of the Study:

  • To review the prevalence, risk factors, and consequences of postpartum depression.
  • To emphasize the crucial role of obstetricians and pediatricians in PPD screening and management.
  • To discuss current treatment options and barriers to care, particularly for breastfeeding mothers.

Main Methods:

  • Literature review of recent research on postpartum depression.
  • Analysis of established short-term and long-term effects on child development.
  • Examination of clinical roles in screening and treatment, including psychotherapy and medication.

Main Results:

  • PPD has significant negative effects on infant and child development.
  • Obstetricians and pediatricians are key figures in identifying and managing PPD.
  • Treatment adherence is hindered by limited access to mental health professionals and concerns regarding infant medication exposure via breast milk.

Conclusions:

  • Effective screening and treatment of PPD by healthcare providers are essential for maternal and child well-being.
  • Addressing barriers to treatment, such as access to care and breastfeeding safety concerns, is critical.
  • Further research is needed on the developmental effects of antidepressant medication transfer through breast milk.