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Updated: Jun 24, 2026
03:23
Three-Dimensional Cell Culture Models to Investigate the Epithelial Barrier in Eosinophilic Esophagitis
Published on: May 10, 2024
Eosinophilic enteritis in association with systemic lupus erythematosus
J Jaimes-Hernandez1, P Aranda-Peirera, C I Melendez-Mercado
1Centro Médico ISSEMYM - División de Medicina Interna, Departamento de Reumatología, San Jerónicmo Chicahualco Metepec Estado de México, Mexico. jorjaimes@yahoo.com
Lupus
|March 26, 2009
Summary
Eosinophilic gastroenteritis (EGE) is rare, especially with systemic lupus erythematosus. This case highlights EGE diagnosis and treatment in a patient with lupus-related symptoms.
Area of Science:
- Gastroenterology
- Rheumatology
- Immunology
Background:
- Eosinophilic gastroenteritis (EGE) is a rare gastrointestinal disorder.
- Association between EGE and connective tissue diseases, like systemic lupus erythematosus (SLE), is infrequently reported.
Observation:
- A 36-year-old woman presented with recurrent abdominal pain, nausea, vomiting, and melena.
- Investigations revealed elevated eosinophils, bowel wall thickening, ascites, pleural effusions, hemolytic anemia, and thrombocytopenia.
- Serological tests showed positive antinuclear antibody and anticardiolipin antibodies.
Findings:
- Diagnosis of EGE was confirmed by eosinophil infiltration in the muscularis propria via mesenteric biopsy.
- The patient exhibited features suggestive of SLE, including positive autoantibodies and pleural effusions.
- High-dose systemic corticosteroid therapy led to symptom resolution.
Implications:
- This case underscores the importance of considering EGE in patients with unexplained gastrointestinal symptoms, particularly those with underlying autoimmune conditions.
- Early diagnosis and appropriate treatment, such as corticosteroids, are crucial for managing EGE and associated complications.
- Further research is warranted to explore the potential link between EGE and systemic lupus erythematosus.
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