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Updated: Jun 24, 2026

Transcranial Pulse Stimulation for Alzheimer's Patients
Published on: April 4, 2025
Persons with moderate Alzheimer's disease improve activities and mood via instruction technology
Giulio E Lancioni1, Nirbhay N Singh, Mark F O'Reilly
1Department of Psychology, University of Bari, Bari, Italy. g.lancioni@psico.uniba.it
Background:
Three studies assessed the (a) effectiveness of verbal instructions presented via technology in helping persons with moderate Alzheimer's disease perform daily activities and (b) impact of activity engagement on mood.
Methods:
The 3 studies targeted coffee preparation with 2 women, use of make-up with 2 women, and use of make-up and tea preparation with 3 women. Intervention effects on activity performance were assessed through nonconcurrent multiple baseline designs across participants or multiple baseline designs across activities. The impact of activity on mood was assessed by recording indices of happiness during activity trials and parallel nonactivity periods.
Results:
Verbal instructions presented via technology were effective in helping all participants perform the target activities. The participants also showed mood improvement (ie, increases in indices of happiness) during the activity.
Conclusion:
These results suggest that the approach reported may be a useful strategy for helping persons with Alzheimer's disease.
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