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A constitutively active GPCR governs morphogenic transitions in Cryptococcus neoformans.

Yen-Ping Hsueh1, Chaoyang Xue, Joseph Heitman

  • 1Department of Molecular Genetics and Microbiology, Duke University, Durham, NC 27710, USA.

The EMBO Journal
|March 27, 2009
PubMed
Summary

A novel constitutively active G protein-coupled receptor, CPR2, governs fungal morphogenesis in Cryptococcus neoformans. This discovery challenges existing paradigms of fungal reproduction and signaling pathways.

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