Related Experiment Video
Updated: Jun 24, 2026

Adjunctive Diode Laser Therapy and Probiotic Lactobacillus Therapy in the Treatment of Periodontitis and Peri-Implant Disease
Published on: May 9, 2022
No difference between full-mouth and quadrant-wise treatment of chronic periodontitis
1Division of Periodontics, Dalhousie University, Halifax, Canada.
Data Sources:
Medline and Embase, along with reference lists from retrieved papers, were used to source relevant studies.
Study Selection:
Only English-language randomised controlled clinical trials (RCT) with at least 6 months followup; that used the patient as the unit of analysis; included patients with chronic periodontitis who had not used antibiotics for 3 months prior to the start of the study; and compared full-mouth debridement or full-mouth disinfection with conventional quadrant root planing were included.
Outcome Measure:
Measures considered were reductions in probing pocket depths, probing attachment levels and bleeding on probing. Study quality was assessed based on randomisation methods, allocation concealment, examiner blinding and completeness of followup.
Data Extraction And Synthesis:
Data were extracted by two reviewers independently and meta-analysis was performed.
Results:
Seven RCT were included. There were no statistically significant differences between the full-mouth debridement and quadrant approaches.
Conclusions:
The review suggests that mechanical or nonsurgical periodontal treatment is effective but showed no difference in the periodontal clinical outcome measures between the full-mouth debridement and quadrant approaches.