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Updated: Jun 24, 2026

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Determining the Functional Status of the Corticospinal Tract Within One Week of Stroke
Published on: February 22, 2020
Functional outcome in poststroke patients with or without fatigue.
Ji Young Park1, Min Ho Chun, Si Hyun Kang
1Department of Rehabilitation Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
American Journal of Physical Medicine & Rehabilitation
|March 28, 2009
Summary
Poststroke fatigue affects 30% of stroke survivors and is linked to depression and sleep issues, not directly to motor or cognitive function. Clinical screening for fatigue and depression is recommended.
Area of Science:
- Neurology
- Rehabilitation Medicine
- Psychiatry
Background:
- Fatigue is a common yet poorly understood complication following stroke.
- The impact of poststroke fatigue on functional recovery remains unclear.
Purpose of the Study:
- To investigate the relationship between poststroke fatigue and functional outcomes.
- To assess the correlation of fatigue with motor, cognitive, and daily living activities in stroke patients.
Main Methods:
- A cohort of 40 stroke outpatients was assessed using the Fatigue Severity Scale (FSS), Modified Barthel Index (MBI), Motricity Index (MI), and Korean-Mini Mental State Examination (K-MMSE).
- Depression was evaluated using the Beck Depression Inventory (BDI), and sleep problems were documented through interviews.
Main Results:
- 30% of stroke patients reported significant poststroke fatigue (FSS score >= 4).
- Fatigue Severity Scale scores were significantly correlated with Beck Depression Inventory scores and sleep disturbances (P < 0.05).
- No significant correlations were found between fatigue and functional outcomes (MBI, MI, K-MMSE).
Conclusions:
- Poststroke fatigue is prevalent and significantly associated with depression and sleep problems.
- Fatigue does not appear to be directly associated with motor, cognitive, or daily living function.
- Clinical assessment should include screening for both fatigue and depression in stroke survivors.
