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Related Concept Videos

Lymphatic Vessels and Lymph Transport01:16

Lymphatic Vessels and Lymph Transport

Lymphatic vessels, known as lymphatics, are crucial in transporting lymph from peripheral tissues to our venous system. This process begins with lymph entering through tiny capillaries that branch through tissues. These capillaries have unique features such as larger diameters, thinner walls, and a distinctive one-way valve system formed by overlapping endothelial cells.
This one-way system allows fluids, solutes, and even pathogens to enter but prevents their return to the intercellular spaces.
Development of the Lymphatic System01:15

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Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

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Functions of the Lymphatic and Immune System01:28

Functions of the Lymphatic and Immune System

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Detailed Structure and Function of Lymph Nodes01:23

Detailed Structure and Function of Lymph Nodes

Lymph nodes are bean-shaped structures that cluster along the lymphatic vessels in the inguinal, axillary, and cervical regions. Each node is divided into compartments by a capsule that extends trabeculae inward.
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Updated: Jun 24, 2026

Non-invasive Optical Imaging of the Lymphatic Vasculature of a Mouse
09:52

Non-invasive Optical Imaging of the Lymphatic Vasculature of a Mouse

Published on: March 8, 2013

[Lymphatic system and lymphoscintigraphy].

Pipitsa Valsamaki1

  • 1Department of Nuclear Medicine, Pammakaristos Hospital, 11144 Athens. pivals@gmail.com

Hellenic Journal of Nuclear Medicine
|March 31, 2009
PubMed
Summary
This summary is machine-generated.

This review covers the history and methods of lymphoscintigraphy, a non-invasive imaging technique for the lymphatic system and sentinel lymph nodes. Nuclear imaging is now used for melanoma and breast cancer, with potential for other solid tumors.

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Visualizing Lymph Node Structure and Cellular Localization using Ex-Vivo Confocal Microscopy
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Last Updated: Jun 24, 2026

Non-invasive Optical Imaging of the Lymphatic Vasculature of a Mouse
09:52

Non-invasive Optical Imaging of the Lymphatic Vasculature of a Mouse

Published on: March 8, 2013

Three-Dimensional Imaging of the Vertebral Lymphatic Vasculature and Drainage using iDISCO+ and Light Sheet Fluorescence Microscopy
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Three-Dimensional Imaging of the Vertebral Lymphatic Vasculature and Drainage using iDISCO+ and Light Sheet Fluorescence Microscopy

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Visualizing Lymph Node Structure and Cellular Localization using Ex-Vivo Confocal Microscopy
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Visualizing Lymph Node Structure and Cellular Localization using Ex-Vivo Confocal Microscopy

Published on: August 9, 2019

Area of Science:

  • Medical Imaging
  • Nuclear Medicine
  • Lymphatic System Research

Background:

  • The lymphatic system's anatomy, physiology, and pathophysiology have been studied since antiquity.
  • Lymphoscintigraphy offers a non-invasive method for visualizing the lymphatic system and identifying sentinel lymph nodes.

Observation:

  • This review details the historical evolution of lymphatic system study and lymphoscintigraphy techniques.
  • It includes descriptions of intra-operative gamma-probe detection and the blue dye method.

Findings:

  • Nuclear imaging methods are integrated into diagnostic and therapeutic strategies for cutaneous melanoma and breast cancer.
  • These techniques aid in precise localization and treatment planning.

Implications:

  • The established role of nuclear methods in melanoma and breast cancer management is highlighted.
  • Further research is needed to explore their application in other solid malignancies for improved patient outcomes.