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Published on: July 9, 2014
Hemorrhagic Pericarditis in a child with primary varicella infection (chickenpox)
B N Nandeesh1, Anita Mahadevan, T C Yasha
1Department of Neuropathology, National Institute of Mental Health and Neurosciences, Bangalore, India.
Insights
Chickenpox (Varicella) can cause severe, fatal complications like hemorrhagic pericarditis and pulmonary thromboembolism, especially in malnourished children. Early recognition and vaccination are crucial for preventing severe outcomes from this common childhood illness.
Area of Science:
- Pediatrics
- Infectious Diseases
- Cardiology
Background:
- Chickenpox (Varicella), a primary Varicella zoster virus infection, is typically a mild childhood illness.
- Complications are uncommon and usually mild, primarily affecting adults and immunocompromised children.
Observation:
- A 5-year-old malnourished girl developed severe complications during a chickenpox infection.
- These complications included hemorrhagic pericarditis and deep vein thrombosis.
Findings:
- The deep vein thrombosis led to a fatal pulmonary thromboembolism.
- This case highlights rare but life-threatening cardiovascular and thromboembolic complications of Varicella.
Implications:
- Malnourished children are at higher risk for severe varicella complications.
- Emphasizes the critical need for Varicella vaccination and prompt identification of complications.
Abstract:
Chickenpox (Varicella) representing the primary infection by Varicella zoster virus is a common benign and self-limited infectious disease of childhood. Although the disease can be associated with complications, they are generally mild and tend to occur in adults and immunocompromised children. Severe and life-threatening complications are extremely rare, particularly those involving the cardiovascular system. We report a malnourished 5-year-old girl with chicken pox complicated by hemorrhagic pericarditis and deep vein thrombosis leading to fatal pulmonary thromboembolism. Though varicella infection runs a benign self-limiting course, it continues to cause significant morbidity and mortality when associated with complications, particularly in malnourished children. Hence, the importance of vaccination and early recognition of complications is emphasized.
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