Genetic differences in hippocampal synaptic plasticity.

S Prakash1, E Ambrosio, L F Alguacil

  • 1Departamento de Farmacología, Tecnología y Desarrollo Farmacéutico, Facultad de Farmacia, Universidad San Pablo CEU, Urb. Montepríncipe, Boadilla del Monte, 28668 Madrid, Spain.

Neuroscience
|April 2, 2009
PubMed
Summary

Genetic background influences synaptic plasticity in rats. Lewis rats show impaired depotentiation after cocaine, unlike Fischer-344 rats, suggesting differing addiction vulnerability.

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