Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Colloids03:22

Colloids

Children at play often make suspensions such as mixtures of mud and water, flour and water, or a suspension of solid pigments in water known as tempera paint. These suspensions are heterogeneous mixtures composed of relatively large particles that are visible to the naked eye or can be seen with a magnifying glass. They are cloudy, and the suspended particles settle out after mixing. On the other hand, a solution is a homogeneous mixture in which no settling occurs and in which the dissolved...
Colloids and Suspensions01:17

Colloids and Suspensions

Children at play often make suspensions such as mixtures of mud and water, flour and water, or a suspension of solid pigments in water known as tempera paint. These suspensions are heterogeneous mixtures composed of relatively large particles visible to the naked eye or seen with a magnifying glass. They are cloudy, and the suspended particles settle out after mixing. The suspended particles in a suspension settle out after some time of mixing. The separation of particles from a suspension is...
The Colloidal State01:29

The Colloidal State

The formation of a colloidal system is exemplified by an aqueous solution containing Cl− ions is introduced to another containing Ag+ ions, resulting in the precipitation of solid AgCl as extremely tiny crystals. Instead of settling out as a filterable precipitate, these crystals remain suspended in the liquid, showcasing a colloidal system.A colloidal system involves colloidal particles within the approximate range of 1 to 1000 nm in at least one dimension, dispersed in a medium called the...
Distribution and Dispersion00:54

Distribution and Dispersion

Ecology is the study of how organisms interact with their environment and with one another. An important aspect of ecology is understanding where species are found and how individuals are distributed within those areas. The geographic range of a species refers to the total area where its members are located, while dispersion describes the pattern of spacing of individuals within that range.Geographic Range and Dispersion PatternsWithin a species’ geographic range, individuals may be distributed...
Factors Affecting Dissolution: Particle Size and Effective Surface Area01:23

Factors Affecting Dissolution: Particle Size and Effective Surface Area

Dissolution kinetics, an essential aspect of oral drug delivery, is significantly influenced by the drug's particle size. According to the Noyes-Whitney dissolution model, the dissolution rate correlates directly with the drug's surface area. The larger the surface area, the higher the drug's solubility in water, leading to a faster drug dissolution rate. Reducing particle size increases the effective surface area, enhancing the dissolution process. Micronization and nanosizing are employed to...
Colloidal precipitates01:09

Colloidal precipitates

The high insolubility of some precipitates can result in an unfavorable relative supersaturation. This can lead to colloidal particles with a large surface-to-mass ratio, where adsorption is promoted. For instance, in the precipitation of silver chloride, silver ions are adsorbed on the surface of the colloidal particles, forming a primary layer. This layer attracts ions of opposite charge (such as nitrate ions), forming a diffuse secondary layer of adsorbed ions. This electric double layer...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Assessment of cost of illness for diabetic patients in South Indian tertiary care hospital.

Journal of pharmacy & bioallied sciences·2017
Same author

Health Related Quality of Life Among Young Smokers.

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research·2016
Same author

Health Related Quality of Life and Medication use Among Young College Students During Menstrual Cycle.

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research·2016
Same author

Perception Pattern Analysis of Self-Medication Practices Among People in Southern District of Karnataka, India.

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research·2016
Same author

Potential Prescriber Mapping In Rural Location Of South India.

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research·2016
Same author

Pharmacoeconomics and its Applications - Emerging Role in India.

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research·2016

Related Experiment Video

Updated: Jun 24, 2026

Dispersion of Nanomaterials in Aqueous Media: Towards Protocol Optimization
09:35

Dispersion of Nanomaterials in Aqueous Media: Towards Protocol Optimization

Published on: December 25, 2017

Solid dispersions: a review.

K Dhirendra1, S Lewis, N Udupa

  • 1Manipal College of Pharmaceutical Sciences, Manipal, Karnataka, India.

Pakistan Journal of Pharmaceutical Sciences
|April 3, 2009
PubMed
Summary

Solid dispersions enhance hydrophobic drug dissolution and bioavailability. This review covers preparation methods, types, characterization, and commercialization challenges for these advanced drug delivery systems.

Area of Science:

  • Pharmaceutical Sciences
  • Drug Delivery Systems

Background:

  • Hydrophobic drugs often exhibit poor solubility, limiting their bioavailability.
  • Solid dispersions offer a promising strategy to overcome these limitations.

Purpose of the Study:

  • To review preparation techniques for solid dispersions.
  • To discuss different types, characterization, and commercialization aspects of solid dispersions.

Main Methods:

  • Literature review of solid dispersion preparation techniques.
  • Analysis of different solid dispersion types based on molecular arrangement.
  • Discussion of practical considerations including carrier selection and physicochemical characterization.

Main Results:

  • Solid dispersions significantly improve drug dissolution rates and bioavailability.

More Related Videos

Challenges in Rheological Characterization of Highly Concentrated Suspensions — A Case Study for Screen-printing Silver Pastes
08:42

Challenges in Rheological Characterization of Highly Concentrated Suspensions — A Case Study for Screen-printing Silver Pastes

Published on: April 10, 2017

Diffuse Reflectance Infrared Spectroscopic Identification of Dispersant/Particle Bonding Mechanisms in Functional Inks
10:31

Diffuse Reflectance Infrared Spectroscopic Identification of Dispersant/Particle Bonding Mechanisms in Functional Inks

Published on: May 8, 2015

Related Experiment Videos

Last Updated: Jun 24, 2026

Dispersion of Nanomaterials in Aqueous Media: Towards Protocol Optimization
09:35

Dispersion of Nanomaterials in Aqueous Media: Towards Protocol Optimization

Published on: December 25, 2017

Challenges in Rheological Characterization of Highly Concentrated Suspensions — A Case Study for Screen-printing Silver Pastes
08:42

Challenges in Rheological Characterization of Highly Concentrated Suspensions — A Case Study for Screen-printing Silver Pastes

Published on: April 10, 2017

Diffuse Reflectance Infrared Spectroscopic Identification of Dispersant/Particle Bonding Mechanisms in Functional Inks
10:31

Diffuse Reflectance Infrared Spectroscopic Identification of Dispersant/Particle Bonding Mechanisms in Functional Inks

Published on: May 8, 2015

  • Various preparation methods and characterization techniques are available.
  • Limited commercialization has been observed, but recent advancements show a revival.

    • Conclusions:

    • Solid dispersions are effective for enhancing the delivery of hydrophobic drugs.
    • Understanding molecular arrangements and practical aspects is crucial for successful formulation.
    • Recent technological advancements are driving renewed interest and commercial potential.