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Updated: Jun 24, 2026
Long-term Lethal Toxicity Test with the Crustacean Artemia franciscana
Published on: April 14, 2012
Occupational allergy to Artemia fish fry feed in aquaculture
Jens-Tore Granslo1, Thien Van Do, Tor B Aasen
1Department of Occupational Medicine, Haukeland University Hospital, Bergen, Norway. jens-tore.granslo@helse-bergen.no
Background:
Artemia (brine shrimp) is used as feed for fish fry and shrimp in aquaculture. Two employees in a Norwegian aquaculture research farm reported having chest symptoms when working in an Artemia hatch room.
Aims:
To determine the presence and prevalence of Artemia sensitization at the farm and the extent of any Artemia-related respiratory and hand skin symptoms and to identify the allergens involved.
Methods:
Participants completed a questionnaire and structured interview. Skin prick tests (SPTs) were performed, and immunoglobulin E (IgE) antibodies to Artemia, shrimp and recombinant tropomyosin were determined. Gel electrophoresis and immunoblots of Artemia extracts were also carried out.
Results:
Thirty of 42 employees (71%) participated. Among the 24 subjects exposed to Artemia, four (17%) reported chest and/or hand skin symptoms during exposure and three of them were IgE sensitized to Artemia. Five (21%) of those exposed demonstrated IgE antibodies to Artemia and four (17%) had immediate-positive SPTs. A serum pool from these subjects exhibited IgE binding to a protein of approximately 97 kDa in the Artemia extract.
Conclusions:
Occupational exposure to the Artemia fish fry feed can cause IgE sensitization and allergic symptoms affecting airways and skin.
