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Updated: Jun 24, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
Psoriasis--a systemic inflammatory disorder: clinic, pathogenesis and therapeutic perspectives
Wolf-Henning Boehncke1, Wolfram Sterry
1Department of Dermatology and Venereology, University of Frankfurt/Main, Frankfurt/Main, Germany. boehncke@em.uni-frankfurt.de
Abstract:
Psoriasis has seen a dramatic change in its perception by dermatologists as well as other medical specialties. Its well-recognized association with several other diseases makes a complete switch in its management necessary. This review summarizes current epidemiological data on the comorbidities of psoriasis. Subsequently, the evidence for insulin resistance as a cause for endothelial cell dysfunction with its relevant pathogenetic link to the development of cardiovascular comorbidity is discussed. Based on these novel insights, we propose a possible state-of-the-art approach towards comprehensive psoriasis management.
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