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Related Experiment Video

Updated: Jun 20, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
11:39

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

Swiss Practice Recommendations for Chronic Prurigo Including Prurigo Nodularis.

Simon M Mueller1, Helmut Beltraminelli2, Wolf-Henning Boehncke3

  • 1Department of Dermatology, University Hospital Basel, Basel, Switzerland.

International Journal of Dermatology
|June 19, 2026
PubMed
Summary

New practice recommendations offer comprehensive guidance for managing chronic prurigo (CPG) and prurigo nodularis (PN). These evidence-based guidelines detail diagnosis and treatment options, including pharmacological and non-pharmacological therapies for better patient outcomes.

Keywords:
Swiss expertschronic prurigochronic prurituspractice recommendationsprurigo nodularis

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The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
11:39

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

Area of Science:

  • Dermatology
  • Clinical Practice Guidelines
  • Therapeutics

Background:

  • Chronic prurigo (CPG), including prurigo nodularis (PN), presents significant management challenges due to its persistent nature and complex treatment landscape.
  • Existing international guidelines for CPG management may be outdated and lack consideration for country-specific nuances.

Purpose of the Study:

  • To develop updated, practical practice recommendations for the diagnosis and treatment of chronic prurigo (CPG).
  • To provide clinicians with comprehensive, evidence-based guidance for managing CPG and PN.

Main Methods:

  • A structured expert consensus process involving twelve specialists.
  • Recommendations were formulated following a standardized literature review and voted upon until at least 75% agreement was reached.
  • GRADE methodology was adapted to include a "Can be considered" category for practical, differentiated guidance.

Main Results:

  • Recommendations cover history taking, diagnostics (laboratory tests, biopsy), questionnaires, general measures, and various therapeutic options.
  • "We recommend" treatments include topical corticosteroids, NB-UVB, dupilumab, and nemolizumab.
  • "We suggest" or "Can be considered" for numerous other therapies like topical calcineurin inhibitors, gabapentinoids, JAK inhibitors, and CBT, while some agents received no recommendation.

Conclusions:

  • These practice recommendations offer comprehensive, up-to-date guidance for the diagnosis and management of CPG and PN.
  • The guidelines aim to support clinicians in Switzerland and internationally in optimizing patient care for chronic prurigo.
  • The consensus process ensured practical, differentiated advice, enhancing clinical decision-making for this challenging condition.