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Updated: Jun 24, 2026

Isolation, Characterization, and Differentiation of Cardiac Stem Cells from the Adult Mouse Heart
Published on: January 7, 2019
Stem cell therapies in cardiovascular disease A "realistic" appraisal
Chohreh Partovian1, Michael Simons
1Angiogenesis Research Center, Section of Cardiology, Departments of Medicine, Pharmacology and Toxicology, Dartmouth-Hitchcock Medical Center, One Medical Center Drive, Lebanon, NH 03756, USA.
Abstract:
The possibility of reconstituting the damaged heart has introduced a new paradigm in cardiovascular biology and created the potential for a new therapeutic approach in the cardiovascular field, where there is a compelling need for innovative treatments. While the results of animal and early clinical studies are encouraging, the more direct use of cell-based therapies in patients is still long-reached. Gaps in our basic understanding of mechanisms, lack of important randomized, double blind, and controlled clinical trials, as well as technology development for cell production are among challenges to be overcome before full translation of cell based therapies in clinical arena. This review focuses on summarizing the latest knowledge in stem cell therapy for cardiovascular diseases.
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