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Refractive errors and strabismus in children with Ddown syndrome: a controlled study
Arsen Akinci1, Ozgur Oner, Ozlem Hekim Bozkurt
1Department of Pediatric Ophthalmology, Diskapi Children's Hospital Ankara, Turkey.
Journal of Pediatric Ophthalmology and Strabismus
|April 7, 2009
Summary
Children with Down syndrome have a significantly higher prevalence of ocular conditions, including refractive errors and strabismus. Early evaluation and treatment are crucial for managing these common vision problems in this population.
Area of Science:
- Ophthalmology
- Genetics
- Pediatrics
Background:
- Down syndrome is associated with a range of health issues, including ocular abnormalities.
- Previous studies indicate a higher risk of vision problems in children with Down syndrome.
Purpose of the Study:
- To determine the prevalence of refractive errors, strabismus, nystagmus, and congenital cataract in children with Down syndrome.
- To compare ocular findings in children with Down syndrome to age-matched control subjects.
Main Methods:
- A cross-sectional study evaluating 77 children with Down syndrome and 151 control subjects.
- Ocular findings were systematically assessed in all participants.
Main Results:
- A high prevalence of ocular findings (97.4%) was observed in children with Down syndrome, compared to 42.4% in controls (P < .0001).
- Nystagmus, strabismus, hypermetropia, astigmatism, and congenital cataract were significantly more common in the Down syndrome group (P < .0001 for most).
Conclusions:
- Children with Down syndrome exhibit a substantially higher prevalence of various ocular and refractive errors.
- Urgent need for comprehensive evaluation, timely treatment, and regular monitoring of visual health in children with Down syndrome.
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