Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Naturalistic Observations02:30

Naturalistic Observations

If you want to understand how behavior occurs, one of the best ways to gain information is to simply observe the behavior in its natural context. However, people might change their behavior in unexpected ways if they know they are being observed. How do researchers obtain accurate information when people tend to hide their natural behavior? As an example, imagine that your professor asks everyone in your class to raise their hand if they always wash their hands after using the restroom. Chances...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Canagliflozin restores electrical properties and suppresses structural damage in isoproterenol-induced myocardial injury models.

Scientific reports·2025
Same author

Egocentric value maps of the near-body environment.

Nature neuroscience·2025
Same author

Conscious and unconscious processes in vision and homeostasis.

Frontiers in behavioral neuroscience·2025
Same author

Rivaroxaban as a Protector of Oxidative Stress-Induced Vascular Endothelial Glycocalyx Damage via the IQGAP1/PAR1-2/PI3K/Akt Pathway.

Journal of vascular research·2024
Same author

Signatures of criticality in efficient coding networks.

Proceedings of the National Academy of Sciences of the United States of America·2024
Same author

Partial chemogenetic inhibition of the locus coeruleus due to heterogeneous transduction of noradrenergic neurons preserved auditory salience processing in wild-type rats.

The European journal of neuroscience·2024
Same journal

Spatial frequency channels implement a mental ruler in spatial vision.

NeuroImage·2026
Same journal

Exploring the Link Between Intravoxel Incoherent Motion Measured Brain Diffusivity During Wakefulness and Sleep Macrostructure in the Elderly.

NeuroImage·2026
Same journal

Closed-loop adaptation of transcranial magnetic stimulation intensity with electroencephalography feedback.

NeuroImage·2026
Same journal

Volumetric postmortem MRI of the medial temporal lobe in Alzheimer's disease and related disorders: methodological advances and implications for in vivo biomarker development.

NeuroImage·2026
Same journal

Neural responses to equity and inequity when receiving vicarious rewards for self and charity during adolescence.

NeuroImage·2026
Same journal

Cognitive Strategy-based neuromodulation optimizes neural communication to improve working memory.

NeuroImage·2026
See all related articles

Related Experiment Video

Updated: Jun 24, 2026

Acute Mouse Brain Slicing to Investigate Spontaneous Hippocampal Network Activity
07:58

Acute Mouse Brain Slicing to Investigate Spontaneous Hippocampal Network Activity

Published on: August 28, 2020

How not to study spontaneous activity.

Nikos K Logothetis, Yusuke Murayama, Mark Augath

    Neuroimage
    |April 7, 2009
    PubMed
    Summary
    This summary is machine-generated.

    This study re-analyzes brain activity data, finding that imperceptible visual flicker, not true rest, influenced previous findings of spontaneous brain activity and slow waves.

    More Related Videos

    A Method for Tracking the Time Evolution of Steady-State Evoked Potentials
    12:03

    A Method for Tracking the Time Evolution of Steady-State Evoked Potentials

    Published on: May 25, 2019

    Induction of an Isoelectric Brain State to Investigate the Impact of Endogenous Synaptic Activity on Neuronal Excitability In Vivo
    10:19

    Induction of an Isoelectric Brain State to Investigate the Impact of Endogenous Synaptic Activity on Neuronal Excitability In Vivo

    Published on: March 31, 2016

    Related Experiment Videos

    Last Updated: Jun 24, 2026

    Acute Mouse Brain Slicing to Investigate Spontaneous Hippocampal Network Activity
    07:58

    Acute Mouse Brain Slicing to Investigate Spontaneous Hippocampal Network Activity

    Published on: August 28, 2020

    A Method for Tracking the Time Evolution of Steady-State Evoked Potentials
    12:03

    A Method for Tracking the Time Evolution of Steady-State Evoked Potentials

    Published on: May 25, 2019

    Induction of an Isoelectric Brain State to Investigate the Impact of Endogenous Synaptic Activity on Neuronal Excitability In Vivo
    10:19

    Induction of an Isoelectric Brain State to Investigate the Impact of Endogenous Synaptic Activity on Neuronal Excitability In Vivo

    Published on: March 31, 2016

    Area of Science:

    • Neuroscience
    • Brain Activity Research
    • Functional Neuroimaging

    Background:

    • The brain exhibits significant intrinsic activity, even without external stimuli.
    • Spontaneous brain activity, or the default mode, is crucial for maintaining bodily functions.
    • Previous studies suggested slow fluctuations in blood-oxygen-level-dependent (BOLD) signals correlate with neuronal activity in the visual cortex.

    Purpose of the Study:

    • To re-analyze electrophysiological and fMRI data from monkey visual cortex.
    • To investigate the influence of experimental conditions on measurements of spontaneous brain activity.
    • To critically evaluate claims of slow wave-like activity in the visual cortex.

    Main Methods:

    • Re-analysis of simultaneous electrophysiological and fMRI data from monkey visual cortex.
    • Examination of power spectral density of neural responses.
    • Analysis of neurovascular impulse response function and spatiotemporal patterns.

    Main Results:

    • The original study's measurements were not conducted during true rest due to undetected visual flicker.
    • This imperceptible flicker significantly altered neural oscillations and the relationship between neural and vascular signals.
    • No evidence of slow waves of activity was found; observed patterns were attributed to signal-to-noise ratio variations.

    Conclusions:

    • Careful selection of experimental protocols is essential for studying spontaneous brain activity.
    • Sensory area activation can influence measurements attributed to spontaneous processes.
    • Previous interpretations of slow waves in visual cortex activity require re-evaluation.