Related Experiment Video
Updated: Jun 24, 2026

Automated Measurement of Cryptococcal Species Polysaccharide Capsule and Cell Body
Published on: January 11, 2018
The structure of Cryptococcus neoformans galactoxylomannan contains beta-D-glucuronic acid
Christian Heiss1, J Stacey Klutts, Zhirui Wang
1Analytical Services/Complex Carbohydrate Research Center, University of Georgia, 315 Riverbend Road, Athens, GA 30602, USA. cheiss@ccrc.uga.edu
Abstract:
The structure of galactoxylomannan, a capsular polysaccharide from the opportunistic yeast Cryptococcus neoformans, was re-examined by NMR spectroscopy and GC-MS. The residue that is 3-linked to the side chain galactose and was previously assigned as beta-D-xylose [Vaishnav, V. V.; Bacon, B. E.; O'Neill, M.; Cherniak, R. Carbohydr. Res.1998, 306, 315-330] was determined to be beta-D-glucuronic acid. A revised structure for this polymer is presented, along with a proposal that this compound be termed glucuronoxylomannogalactan (GXMGal).
Related Concept Videos
Oligosaccharide Assembly
Multiple sugar molecules that may or may...
Cryptococcal Meningitis
Proteoglycans
Protein Glycosylation
Glycosylation occurs in...
Antifungal Agents
Glycocalyx and its Functions
Components of...

