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Updated: Jun 24, 2026

Design and Implementation of an fMRI Study Examining Thought Suppression in Young Women with, and At-risk, for Depression
Published on: May 19, 2015
Depressive cognition: self-reference and depth of processing
1Yale University, Department of Psychology, Box 208205, New Haven, CT 06520-8205, USA. Blair.wisco@yale.edu
Abstract:
Cognitive models of depression, which propose that depression is associated with negatively biased thinking, have typically focused on either the content or the processes of depressive cognition. Content-based models suggest that depressive thought is more negative for self-relevant than for externally-focused content. Process-based models propose that early, automatic processes are not negatively biased in depression, but that deeper processes are biased. The current review evaluates evidence for both the self-relevant content and depth of processing accounts, and concludes that there is substantial evidence for both models. I call for further research which integrates content and process-based approaches by using self-relevant stimuli and cognitive measures which precisely identify the specific attention, memory, and interpretation processes affected in depression.
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