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Related Concept Videos

Homeostatic Imbalances in Body Temperature01:19

Homeostatic Imbalances in Body Temperature

Hyperthermia occurs when the body's temperature becomes unusually high, often due to heat exposure, intense physical activity, or certain illnesses. This condition can create a dangerous cycle where elevated body temperature increases the metabolic rate, generating more heat and potentially leading to organ failure and brain damage. A severe form of hyperthermia, called heat stroke, can raise body temperature to life-threatening levels. Fever, on the other hand, is a controlled form of...
Types of Fever01:25

Types of Fever

Fever can be triggered by several factors, including infections, nervous system disorders, certain cancers, blood diseases like leukemia, embolism, thrombosis, heatstroke, dehydration, surgical trauma, crushing injuries, and allergic reactions.
Here are the different types of fever:
Increased Body Temperature01:25

Increased Body Temperature

A body temperature above  38°C  (100.4 °F) is known as fever or pyrexia, and a person with fever is termed 'febrile.' Typically, the hypothalamus, a part of the brain that acts as the body's thermostat, regulates body temperature through a thermoregulatory setpoint. It receives signals from cold and warm thermal receptors throughout the body and adjusts the body's temperature accordingly. Fever occurs when this hypothalamic setpoint is altered, usually in response to an infection or illness.
Hyperthyroidism II: Pathophysiology01:27

Hyperthyroidism II: Pathophysiology

Hyperthyroidism is a hypermetabolic state caused by elevated levels of thyroid hormones, triiodothyronine (T3) and thyroxine (T4). It results from dysregulation at the thyroid, pituitary, or immune system level and affects multiple organ systems.PathophysiologyThe most common cause of hyperthyroidism is Graves’ disease, an autoimmune disorder in which antibodies, specifically thyroid-stimulating antibodies (TSAb), a subtype of TSH receptor antibodies (TRAb), bind to and activate TSH receptors...
Hyperthyroidism I: Introduction01:25

Hyperthyroidism I: Introduction

Hyperthyroidism is a type of thyrotoxicosis characterized by the thyroid gland's overproduction of the thyroid hormones triiodothyronine (T3) and thyroxine (T4). This hormone excess increases the basal metabolic rate and enhances sensitivity to catecholamines.DiagnosisDiagnosis is based on clinical features and biochemical testing. It typically shows suppressed thyroid-stimulating hormone (TSH) levels below 0.4 mIU/L, with elevated free T3 and/or T4. Additional tests, including thyroid...
Decreased Body Temperature01:29

Decreased Body Temperature

A decreased body temperature can occur in patients with hypothermia and frostbite. Heat loss with extended cold exposure overpowers the body's ability to create heat, resulting in hypothermia. Core temperature readings help classify hypothermia. Mild hypothermia is temperatures between 32 °C (89.6 °F) and 35°C (95 °F) and is caused by impaired thermoregulation. Moderate hypothermia is temperatures between 28 C (82.4 °F) and 32 °C (89.6 °F) caused by sustained extreme cold exposure, and severe...

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Pulse pressure variability is associated with unfavorable outcomes in acute ischaemic stroke patients treated with intravenous thrombolysis.

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Related Experiment Video

Updated: Jun 24, 2026

Protocol for Long Duration Whole Body Hyperthermia in Mice
07:56

Protocol for Long Duration Whole Body Hyperthermia in Mice

Published on: August 25, 2012

[Malignant hyperthermia and its differential diagnosis].

K Hüttemann1, T Nowe, M Köhrmann

  • 1Neurologische Klinik der Universität Erlangen, Erlangen. Katrin.Huettemann@uk-erlangen.de

Fortschritte Der Neurologie-Psychiatrie
|April 7, 2009
PubMed
Summary

This review covers malignant hyperthermia, serotonin syndrome, and neuroleptic malignant syndrome, detailing their symptoms, causes, and treatments. It aims to help clinicians differentiate these critical hyperthermic conditions.

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Magnetic Resonance-Guided High Intensity Focused Ultrasound Generated Hyperthermia: A Feasible Treatment Method in a Murine Rhabdomyosarcoma Model
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Magnetic Resonance-Guided High Intensity Focused Ultrasound Generated Hyperthermia: A Feasible Treatment Method in a Murine Rhabdomyosarcoma Model

Published on: January 13, 2023

Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management
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Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management

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Related Experiment Videos

Last Updated: Jun 24, 2026

Protocol for Long Duration Whole Body Hyperthermia in Mice
07:56

Protocol for Long Duration Whole Body Hyperthermia in Mice

Published on: August 25, 2012

Magnetic Resonance-Guided High Intensity Focused Ultrasound Generated Hyperthermia: A Feasible Treatment Method in a Murine Rhabdomyosarcoma Model
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Magnetic Resonance-Guided High Intensity Focused Ultrasound Generated Hyperthermia: A Feasible Treatment Method in a Murine Rhabdomyosarcoma Model

Published on: January 13, 2023

Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management
06:43

Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management

Published on: November 21, 2017

Area of Science:

  • Neurology
  • Internal Medicine
  • Pharmacology

Context:

  • Hyperthermia significantly impacts cardiovascular and central nervous systems, potentially causing severe complications.
  • Neurological hyperthermic syndromes pose diagnostic challenges in clinical practice.

Purpose:

  • To review the signs, symptoms, pathophysiology, and therapeutic strategies for three common neurological hyperthermic syndromes.
  • To facilitate differential diagnosis among malignant hyperthermia, serotonin syndrome, and neuroleptic malignant syndrome.
  • To explore associations between other myopathies and hyperthermia syndromes.

Summary:

  • This review details malignant hyperthermia, serotonin syndrome, and neuroleptic malignant syndrome, emphasizing their clinical presentations, underlying mechanisms, and management options.
  • It provides a comparative analysis to aid in distinguishing these critical conditions.
  • The review also touches upon related myopathies and hyperthermia.

Impact:

  • Enhances clinical recognition and differential diagnosis of life-threatening hyperthermic syndromes.
  • Improves patient outcomes through timely and accurate diagnosis and treatment.
  • Contributes to the understanding of complex hyperthermia pathophysiology in neurological contexts.