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Related Concept Videos

Peripheral Artery Disease III: Interprofessional Care01:27

Peripheral Artery Disease III: Interprofessional Care

Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
Peripheral Artery Disease IV: Nursing Management01:26

Peripheral Artery Disease IV: Nursing Management

The nursing management of a patient with peripheral artery disease (PAD) begins with a thorough assessment of the patient’s health history and clinical manifestations.AssessmentHealth History: Evaluate the patient’s history of hypertension, hyperlipidemia, family history of cardiovascular issues, and lifestyle factors such as dietary patterns, smoking, and physical activity.Physical Examination:Assess the affected extremity for decreased or absent peripheral pulses, temperature changes,...
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation01:21

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
Peripheral Artery Disease V: Postoperative Nursing Management01:23

Peripheral Artery Disease V: Postoperative Nursing Management

During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
Peripheral Artery Disease I: Introduction01:30

Peripheral Artery Disease I: Introduction

Peripheral artery disease (PAD) predominantly results from atherosclerosis, which involves the accumulation of fatty deposits, or plaques, within the walls of arteries. This causes them to narrow and harden, significantly reducing blood flow. PAD predominantly affects the legs, particularly the arteries supplying the thighs and calves. In rare cases, it may involve other arteries, including those in the arms.Etiology of PAD:The principal cause of PAD is atherosclerosis, which results from fatty...
Ischemic Heart Disease: Overview01:17

Ischemic Heart Disease: Overview

Ischemic heart disease occurs when the heart's blood supply dwindles, causing an ominous lack of oxygen and nutrients. This deficiency, stemming from reduced or obstructed blood flow, spells danger, leading to heart muscle damage and dysfunction.
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and narrowing...

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Related Experiment Video

Updated: Jun 24, 2026

High-Resolution Three-Dimensional Imaging of the Footpad Vasculature in a Murine Hindlimb Gangrene Model
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Published on: March 16, 2022

[Critical lower limb ischemia as a future challenge].

Anders Albäck1, Maarit Venermo, Pirkka Vikatmaa

  • 1HYKS:n verisuonikirurgian klinikka PL 340, 00029 HUS.

Duodecim; Laaketieteellinen Aikakauskirja
|April 11, 2009
PubMed
Summary

Critical lower limb ischemia affects thousands annually in Finland. Advances in vascular reconstruction and endovascular procedures are reducing amputation rates, improving limb viability.

Area of Science:

  • Vascular Surgery
  • Ischemia Research
  • Public Health

Background:

  • Critical lower limb ischemia (CLI) is a severe condition characterized by chronic hypoxia, endangering limb viability.
  • CLI affects 2,600 to 5,300 individuals in Finland annually.
  • An aging population and rising diabetes incidence are projected to increase CLI prevalence.

Purpose of the Study:

  • To analyze trends in CLI treatment in Finland.
  • To evaluate the impact of vascular reconstruction and endovascular procedures on amputation rates.
  • To understand the evolving landscape of CLI management.

Main Methods:

  • Retrospective analysis of epidemiological data on CLI in Finland.
  • Review of treatment modalities, including vascular reconstructions and endovascular interventions.

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Methods for Acute and Subacute Murine Hindlimb Ischemia
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Methods for Acute and Subacute Murine Hindlimb Ischemia

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High-Resolution Three-Dimensional Imaging of the Footpad Vasculature in a Murine Hindlimb Gangrene Model
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Predicting Amputation using Local Circulating Mononuclear Progenitor Cells in Angioplasty-treated Patients with Critical Limb Ischemia
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Methods for Acute and Subacute Murine Hindlimb Ischemia
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Methods for Acute and Subacute Murine Hindlimb Ischemia

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  • Comparison of amputation rates over the last decade.

    • Main Results:

    • A decrease in lower limb amputations has been observed.
    • An increase in the utilization of vascular reconstructions for limb salvage.
    • Endovascular procedures are increasingly employed for treating blood vessel occlusions and stenoses.

    Conclusions:

    • Vascular reconstructions and endovascular techniques are effective in reducing amputations for CLI.
    • The shift towards less invasive endovascular treatments is a key trend in managing CLI.
    • Improved treatment strategies are enhancing limb viability in patients with critical lower limb ischemia.