Related Experiment Video
Updated: Jun 24, 2026

Transradial Access Chemoembolization for Hepatocellular Carcinoma Patients
Published on: September 20, 2020
Use of slender catheters for transradial angiography and interventions
Motomaru Masutani1, Fuminobu Yoshimachi, Takashi Matsukage
1Hyogo College of Medicine, Nishinomiya, Japan. moto-maru@nifty.com
Insights
The Slender System, featuring smaller guidewires and catheters, offers a viable alternative for complex coronary interventions like bifurcation lesions and chronic total occlusions (CTO), reducing complications associated with larger devices.
Area of Science:
- Interventional Cardiology
- Medical Device Technology
- Vascular Surgery
Background:
- Current coronary interventions commonly use 0.014-inch guidewires and 6-F or 7-F guiding catheters.
- Larger guiding catheters (6-F/7-F) are associated with increased punctured-site complications and potential radial artery occlusion.
- The transradial approach, while safer than transfemoral, can still lead to complications with larger catheters.
Purpose of the Study:
- To evaluate the efficacy and safety of the novel "Slender System" for complex coronary interventions.
- To assess the feasibility of using smaller diameter devices (0.010-inch guidewires, 5-F guiding catheters, 3-F angiography catheters) for bifurcation lesions and chronic total occlusions (CTO).
- To compare outcomes of the Slender System with traditional larger-bore systems.
Main Methods:
- Utilized a "Slender System" comprising 0.010-inch guidewires, 5-F guiding catheters, and 3-F angiography catheters.
- Performed Kissing Balloon Technique (KBT) with the Slender System for bifurcation lesions.
- Applied the Slender System for the treatment of chronic total occlusions (CTOs) via a transradial approach.
- Described angiography procedures using a 3-F catheter.
Main Results:
- The Slender System was used in 96% of transradial chronic total occlusion (CTO) cases.
- Successful treatment with the Slender System alone was achieved in 68% of CTO cases.
- The overall success rate for CTO treatment using the Slender System was 89%.
Conclusions:
- Complex lesions, including bifurcation lesions and CTOs, can be effectively treated using the Slender System.
- The Slender System demonstrates that not all complex coronary interventions necessitate larger guiding catheters (≥6-F), femoral approaches, or bilateral guiding catheters.
- This approach may reduce punctured-site complications and improve patient outcomes in interventional cardiology.
Abstract:
Currently the 0.014-inch guidewire is commonly used for coronary intervention and all devices are 0.014 inch-compatible. The size of common guiding catheters is 6-F or 7-F. However, PCI requires oral administration of antiplatelet agents, and punctured-site complications such as hemorrhage and hematoma occur more frequently with use of a 6-F or 7-F guiding catheter compared to a 5-F guiding catheter. Moreover, 6-F or larger guiding catheters may cause radial arterial occlusion, although the transradial approach causes less punctured-site complications compared to the transfemoral approach. Recently, 0.010-inch guidewires applicable for the Kissing Balloon Technique (KBT) using a 5-F guiding catheter and 0.010-inch guidewire-compatible balloons have been developed in Japan, and a 3-F angiography catheter has also been developed. We refer to these devices as the "Slender System", and we have used this system for active treatment of bifurcation lesions and chronic total occlusion (CTO). In this report, we describe angiography using a 3-F catheter, the KBT using a 5-F guiding catheter and 0.010-inch guidewires, and treatment of CTO using a 5-F catheter and 0.010-inch guidewires. For CTO treated using the Slender System at our facility, the transradial arterial approach was used in 96% of cases, treatment using the Slender System alone succeeded in 68%, and the overall success rate was 89%. Therefore, our results show that complex lesions may be treatable using the Slender System, and that not all complex lesions require a 6-F or larger guiding catheters, a femoral arterial approach, or bilateral guiding catheters.
More Related Videos
13:48Reduction of Radiation Exposure during Endovascular Treatment of Peripheral Arterial Disease Combining Fiber Optic RealShape Technology and Intravascular Ultrasound
Published on: April 21, 2023
10:28Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
Published on: March 15, 2022
Related Concept Videos
Cardiac Catheterization IV: Nursing Management
Cardiac Catheterization III: Left Heart Catheterization
Cardiac Catheterization I: Pre-Procedure Overview
Imaging Studies VII: Vascular Imaging
Peripheral Artery Disease III: Interprofessional Care
Cardiac Catheterization II: Right Heart Catheterization