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Enteroviruses other than poliovirus.

R Kono

    Bulletin of the Pan American Health Organization
    |January 1, 1976
    PubMed
    Summary

    Enteroviruses, particularly Coxsackievirus B, are linked to viral heart disease. Other enteroviruses are implicated in nephritis, diabetes, and hemorrhagic conjunctivitis, with Enterovirus 70 causing a pandemic eye infection.

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    Area of Science:

    • Virology
    • Infectious Diseases
    • Public Health

    Background:

    • Enteroviruses are a group of viruses known to cause various human illnesses.
    • Their association with specific diseases like cardiac conditions, nephritis, diabetes, and conjunctivitis requires detailed examination.

    Purpose of the Study:

    • To review the established and suspected roles of enteroviruses in specific diseases.
    • To highlight the causative agents and epidemiological patterns of these enteroviral infections.

    Main Methods:

    • Literature review of documented cases and etiological studies.
    • Analysis of viral typing and disease association data.

    Main Results:

    • Coxsackievirus B (CBV) types 1-5 are primary causes of viral heart disease; Coxsackievirus A and echoviruses are also implicated.
    • Enteroviruses, particularly CBV 3 and 4, are suspected in nephritis, pancreatitis, and diabetes, though evidence is controversial.
    • Enterovirus 70 is the confirmed cause of a pandemic hemorrhagic conjunctivitis, with potential neurovirulence and risk of motor paralysis.

    Conclusions:

    • Enteroviruses play a significant role in diverse human pathologies, notably viral myocarditis.
    • Further research is necessary to clarify the controversial links between enteroviruses and metabolic/renal diseases.
    • Enterovirus 70 represents a significant global health concern due to its rapid spread and potential neurological complications.

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