Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Video

Updated: Jun 24, 2026

Generation of Size-controlled Poly (ethylene Glycol) Diacrylate Droplets via Semi-3-Dimensional Flow Focusing Microfluidic Devices

Generation of Size-controlled Poly (ethylene Glycol) Diacrylate Droplets via Semi-3-Dimensional Flow Focusing Microfluidic Devices

Published on: July 3, 2018

Bubble formation dynamics in various flow-focusing microdevices.

N Dietrich¹, S Poncin, N Midoux

¹Laboratoire des Sciences du Génie Chimique, Nancy-Université, CNRS 1 rue Grandville, BP 20451, 54000 Nancy Cedex, France.

Langmuir : the ACS Journal of Surfaces and Colloids

|April 11, 2009

Summary

This study explores bubble formation in gas-liquid micromixers, finding that geometry significantly impacts bubble size. A new correlation helps estimate bubble size based on flow rates and fluid properties.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Patterns and Predictors of Prostate-Specific Membrane Antigen Positron Emission Tomography/Computed Tomography-Detected Local Recurrence Following Postprostatectomy Salvage Radiotherapy for Prostate Cancer.

Clinical oncology (Royal College of Radiologists (Great Britain))·2026

Same author

Spreading dynamics of drops on a solid surface submerged in different outer fluids.

Journal of colloid and interface science·2025

Same author

Dimensionality reduction of high-solid anaerobic digestion flow pattern: Flow velocity distribution model and control strategy.

Bioresource technology·2024

Same author

A microscale system for <i>in situ</i> investigation of immobilized microalgal cell resistance against liquid flow in the early inoculation stage.

Lab on a chip·2023

Same author

Coalescence of a Ferrofluid Drop at Its Bulk Surface with or without a Magnetic Field.

Langmuir : the ACS journal of surfaces and colloids·2022

Same author

[First 18 months as certified ERAS® center for colorectal cancer : Lessons learned and results of the first 261 patients].

Chirurgie (Heidelberg, Germany)·2022

Area of Science:

Fluid Dynamics
Microfluidics
Chemical Engineering

Background:

Understanding microscale gas-liquid flow is crucial for various applications.
Existing research often lacks detailed flow field characterization in micromixers.
Flow-focusing devices require optimized designs for efficient bubble generation.

Purpose of the Study:

To investigate bubble formation in three distinct gas-liquid micromixer geometries.
To analyze the influence of mixer geometry, flow rates, and fluid properties on bubble characteristics.
To develop a correlation for predicting bubble size in microscale flow-focusing devices.

Main Methods:

Utilized micro particle image velocimetry (PIV) for flow field characterization.
Employed high-speed cameras for visualizing and analyzing bubble formation dynamics.

More Related Videos

Capillary-based Centrifugal Microfluidic Device for Size-controllable Formation of Monodisperse Microdroplets

Capillary-based Centrifugal Microfluidic Device for Size-controllable Formation of Monodisperse Microdroplets

Published on: February 22, 2016

Related Experiment Videos

Last Updated: Jun 24, 2026

Generation of Size-controlled Poly (ethylene Glycol) Diacrylate Droplets via Semi-3-Dimensional Flow Focusing Microfluidic Devices

Generation of Size-controlled Poly (ethylene Glycol) Diacrylate Droplets via Semi-3-Dimensional Flow Focusing Microfluidic Devices

Published on: July 3, 2018

Capillary-based Centrifugal Microfluidic Device for Size-controllable Formation of Monodisperse Microdroplets

Capillary-based Centrifugal Microfluidic Device for Size-controllable Formation of Monodisperse Microdroplets

Published on: February 22, 2016

Conducted experiments across varied flow rates, liquid properties, and micromixer designs.

Main Results:

Bubble formation and size are significantly dependent on the micromixer geometry.
Identified key parameters influencing bubble dynamics, including flow rate ratio, surface tension, and viscosity.
Developed a novel correlation to accurately estimate bubble size using experimental data.

Conclusions:

Micromixer geometry is a critical factor in controlling bubble size and formation.
The developed correlation provides a valuable tool for designing and optimizing microfluidic devices.
This study offers original flow field insights and predictive models for gas-liquid flow-focusing devices.