Intrascrotal sarcoidosis in a pediatric patient

Sarcoidosis is a granulomatous disease with diverse skin manifestations and systemic involvement. We describe an adolescent boy who presented with unilateral scrotal swelling, constitutional symptoms, and a rash. Further workup demonstrated lymphadenopathy and pulmonary opacities. Granulomas caused by sarcoidosis were identified in biopsy specimens of the epididymis and skin lesions. No acid-fast organisms were found in biopsy specimens, and the patient had negative findings on placement of purified protein derivative (tuberculin). The concentration of angiotensin-converting enzyme was not elevated. We discuss pediatric sarcoidosis and, more specifically, intrascrotal sarcoidosis.