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Lymph nodes in hidradenitis suppurativa
Ximena Wortsman1, Jean Revuz, Gregor B E Jemec
1Radiology Department, Hospital del Profesor and Clínica Servet, Santiago de Chile, Chile.
Dermatology (Basel, Switzerland)
|April 15, 2009
Summary
Hidradenitis suppurativa (HS) involves inflammation, but lymph nodes are rarely felt. Ultrasound revealed enlarged lymph nodes only in late-stage HS, suggesting secondary infection rather than a primary cause.
Area of Science:
- Dermatology
- Medical Imaging
Background:
- Hidradenitis suppurativa (HS) is an inflammatory skin condition.
- Palpable lymphadenopathy is uncommon in HS patients, potentially due to disease obscuring nodes or lack of swelling.
Purpose of the Study:
- To investigate regional lymph node characteristics in HS patients using ultrasound.
- To compare lymph node size and number between HS patients and healthy controls.
Main Methods:
- High-resolution ultrasound was employed to scan axillary and inguinal lymph nodes in HS patients and controls.
- Lymph node morphology, number, and diameter were assessed.
Main Results:
- No significant difference in lymph node number or overall mean diameter was observed between HS patients and controls.
- Significantly increased mean lymph node diameter was found in Hurley stage III HS patients (1.3 ± 0.4 cm, p=0.03).
Conclusions:
- Lymph node enlargement in HS appears to be associated with advanced disease stages (Hurley stage III).
- This finding suggests lymph node involvement may indicate secondary infection rather than a primary etiological factor in HS.
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