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Updated: Jun 24, 2026

Fractionation for Resolution of Soluble and Insoluble Huntingtin Species
Published on: February 27, 2018
[Suicide in Huntington's disease: a review]
L Bindler1, D Travers, B Millet
1Université de Rennes-I, Service hospitalo-universitaire de psychiatrie adulte, Centre hospitalier Guillaume Régnier, 108, av. du Général Leclerc, BP 60321-35703 Rennes cedex 7, France. louis.b.67@hotmail.fr
Insights
Huntington's disease patients exhibit a fourfold increase in suicide rates compared to the general population. Addressing psychiatric care needs is crucial for preventing suicidal behaviors in these individuals.
Area of Science:
- Neurodegenerative Diseases
- Psychiatry
- Suicidology
Context:
- Huntington's disease (HD) is a progressive neurodegenerative disorder.
- Suicide is a significant concern in patients with HD.
- Existing literature highlights elevated suicide risk in HD populations.
Purpose:
- To review key findings on suicide in Huntington's disease.
- To identify risk factors and protective measures for suicide in HD patients.
- To underscore the importance of psychiatric interventions for HD.
Summary:
- A review of studies indicates a four times higher incidence of suicide among Huntington's disease patients than in the general population.
- Lack of offspring and inadequate psychological support are potential risk factors.
- Proactive and appropriate psychiatric care is essential for suicide prevention in HD.
Impact:
- Highlights the critical need for specialized mental health support for Huntington's disease patients.
- Informs clinical practice regarding suicide risk assessment and management in neurodegenerative disorders.
- Contributes to a better understanding of the psychosocial aspects of Huntington's disease.
Abstract:
This paper aims at providing a selective review of the major issues and findings concerning suicide in Huntington's disease. Most of the authors found a four times higher suicidal occurrence in Huntington patients than in the general population. No specific individual risk factor was found except the lack of offspring and psychological support. This paper emphasizes the need of appropriate psychiatric cares for Huntington patients in order to prevent, as much as possible, their suicidal behaviors.
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