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Updated: Jun 24, 2026

Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission
07:16

Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission

Published on: August 16, 2018

Modulation of receptor sensitivity: possible therapeutic target?

Michel V Cohen1, James M Downey

  • 1Department of Physiology, University of South Alabama, College of Medicine, Mobile, AL 36688, USA. mcohen@usouthal.edu

British Journal of Pharmacology
|April 16, 2009
PubMed
Summary

Ischaemic preconditioning and post-conditioning protect the heart by blocking surface receptor desensitization, a novel effect separate from their known cardioprotective benefits. Further research is needed to explore clinical applications for acute myocardial infarction treatment.

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