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Updated: Jun 19, 2026

Staining Protocols for Human Pancreatic Islets
Published on: May 23, 2012
Human pancreatic islets and diabetes research
John S Kaddis1, Barbara J Olack, Janice Sowinski
1Department of Information Sciences, City of Hope National Medical Center, 1500 E Duarte Rd, Duarte, CA 91010-3000, USA. jkaddis@coh.org
The national Islet Cell Resource Center Consortium provides vital human islets for diabetes research, supporting scientists and advancing therapeutic options. This resource highlights the critical role of human islet research in understanding pancreatic cellular biology and combating diabetes.
Area of Science:
- Endocrinology
- Cell Biology
- Diabetes Research
Background:
- Human islet research is essential for understanding pancreatic cellular biology.
- Developing therapeutic options and prevention strategies for diabetes requires this research.
- The Islet Cell Resource Center Consortium was established to support this critical need.
Purpose of the Study:
- To highlight the importance of the national Islet Cell Resource Center Consortium.
- To demonstrate the value of human islets in diabetes research.
- To discuss the role of islet distribution centers and future directions.
Main Methods:
- The study reviews data on islet distribution, quality, and usage.
- It analyzes the impact of supplied islets on funded grants and publications.
- The study also discusses limitations and future prospects of islet distribution.
Main Results:
- Since 2001, the consortium supplied 297.6 million islet equivalents to 151 scientists.
- Data confirm the significance of human islets for diabetes research.
- Numerous grants and publications resulted from the use of these islets.
Conclusions:
- Human islets are indispensable for advancing diabetes research and developing treatments.
- The Islet Cell Resource Center Consortium plays a crucial role in facilitating this research.
- Understanding limitations and future needs is key for continued progress in islet distribution and diabetes care.
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