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Pipe Flowrate Measurement

Pipe Flowrate Measurement

In pipe flow measurement, orifice, nozzle, and Venturi meters are commonly used to determine fluid flowrates by constricting the flow area, which increases fluid velocity and reduces pressure. This pressure difference, governed by Bernoulli's principle and adjusted for real-world conditions, is essential for calculating flowrate. Each meter type is suited to specific applications based on accuracy, efficiency, and compatibility with various flow conditions.
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In Situ Microscopy for Real-time Determination of Single-cell Morphology in Bioprocesses

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Published on: December 5, 2019

Soft microflow sensors.

Rafaele Attia¹, Daniel C Pregibon, Patrick S Doyle

¹Laboratoire Physicochimie Curie, CNRS/UMR 168, 11 rue Pierre et Marie Curie, Paris, France. rafaele.attia@curie.fr

|April 17, 2009

Summary

This summary is machine-generated.

This study introduces a new method for creating functional microfluidic devices using stop-flow lithography. This technique enables the fabrication of adaptable microflow sensors with a wide dynamic range for precise flow measurements.

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Area of Science:

Microfluidics
Materials Science
Mechanical Engineering

Background:

Conventional polydimethylsiloxane (PDMS) microfluidic devices often lack integrated functional components.
Rapid prototyping methods are needed to enhance the capabilities of PDMS microfluidic systems.

Purpose of the Study:

To develop a rapid prototyping method for integrating functional components into PDMS microfluidic devices.
To fabricate microflow sensors with controlled mechanical properties and a large dynamic range.

Main Methods:

Utilized stop-flow lithography for in situ fabrication of mobile and deformable elements.
Designed and fabricated microflow sensors based on a deformable spring-like structure.
Employed a simple hydrodynamic model to analyze sensor flow-elongation characteristics.

Main Results:

Demonstrated successful integration of functional components in PDMS microfluidic devices.
Developed microflow sensors exhibiting a large dynamic range (3-4 orders of magnitude).
Achieved accurate flow measurements in the nanoliter per minute range.
Showed good agreement between experimental data and hydrodynamic modeling.

Conclusions:

Stop-flow lithography is an effective method for rapid prototyping of functional microfluidic components.
The developed microflow sensors offer high sensitivity and a broad dynamic range for microfluidic applications.
Hydrodynamic modeling provides a reliable approach for characterizing the performance of these deformable sensors.