Related Experiment Video
Updated: Jun 23, 2026

Endoscopic Injection Sclerotherapy Assisted by Cyanoacrylate and Clips for Gastroesophageal Varices
Published on: June 13, 2025
Variceal bleeding from ileum identified and treated by single balloon enteroscopy
Mario Traina1, Ilaria Tarantino, Luca Barresi
1Istituto Mediterraneo Trapianti e Terapie ad Alta Specializzazione, Italy. itarantino@ismett.edu
This study presents a case of severe gastrointestinal bleeding in a liver cirrhosis patient. Single-balloon enteroscopy successfully identified and treated ileal varices using a freehand sclerosant injection technique.
Area of Science:
- Gastroenterology
- Hepatology
- Endoscopy
Background:
- Liver cirrhosis frequently leads to gastrointestinal bleeding, often from esophageal varices.
- Small bowel varices are a less common but significant cause of obscure gastrointestinal bleeding.
Observation:
- A patient with liver cirrhosis presented with acute, uncontrolled gastrointestinal bleeding.
- Standard upper and lower endoscopic evaluations did not identify the bleeding source.
Findings:
- Single-balloon enteroscopy enabled detailed examination of the small bowel.
- Bleeding varices in the ileum were identified as the source of hemorrhage.
- A freehand injection technique using a sclerosant solution was successfully employed via single-balloon enteroscopy for treatment.
Implications:
- Single-balloon enteroscopy is a valuable tool for diagnosing obscure gastrointestinal bleeding in cirrhosis.
- Freehand sclerosant injection is a feasible treatment for small bowel varices.
- This approach offers a potential therapeutic option for managing refractory gastrointestinal bleeding in liver disease.
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