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A new chalcone from Pongamia pinnata and its antioxidant properties
Anindita Ghosh1, Suvra Mandal, Avijit Banerji
1Centre of Advanced Studies on Natural Products including Organic Synthesis, Department of Chemistry, Calcutta University, 92 A.P.C. Road, Kolkata-700 009, India.
Abstract:
The root bark of Pongamia pinnata Pierre [syn P. glabra (family: Fabaceae)] afforded a new chalcone (karanjapin) and two known flavonoids, a pyranoflavonoid (karanjachromene) and a furanoflavonoid (karanjin) The structure of karanjapin has been established from extensive 2D NMR spectral studies as beta,2'-dihydroxy-a,4'-dimethoxy-3,4-methylenedioxychalcone. Karanjapin and karanjachromene were found to possess significant antioxidant activity. This may play an important role in the pathogenesis of several diseases.
