Antimony(III) chloride catalyzed direct three component one-pot Mannich reaction

Prashant Shukla1, Nilmadhab Chattopadhyay, Sandip K Nayak

  • 1Bio-Organic Division, Bhabha Atomic Research Centre, Mumbai-400085, India.

Summary

Antimony(III) chloride efficiently catalyzes a three-component Mannich reaction. This process yields beta-amino ketones from Schiff bases and ketones at room temperature with good results.

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