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Updated: Jun 23, 2026

Microbiological Rapid On-Site Evaluation for Pulmonary Infectious Diseases
Published on: March 1, 2024
Purpura fulminans secondary to respiratory infection
Antje Jakob1, Elias Alexandrakis, Rainer Rompel
1Department of Dermatology, Clinic Kassel, Mönchebergstrasse 41-43, Kassel, Germany. jakob@klinikum-kassel.de
Abstract:
Purpura fulminans features the sudden onset of large rapidly-spreading areas of hemorrhagic skin necrosis. This is followed by a disseminated intravascular coagulopathy with consecutive consumption of anticoagulant factors. Patients with severe disease in whom therapy is delayed often develop shock with a poor prognosis.The mortality rate is about 30-40%. An elderly women developed purpura fulminans after a respiratory infection. Prompt diagnosis before shock symptoms had started was instrumental in producing a favorable clinical course.
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