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Updated: Jun 23, 2026

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
Published on: December 11, 2017
[Role of cardiac resynchronization therapy for treatment of heart failure]
1Service de médecine interne, HUG, 1211 Genève 14.
Abstract:
Cardiac resynchronization therapy by a biventricular pacemaker or defibrillator is recommended for treating selected patients with systolic heart failure who are in NYHA class III or IV despite optimal medical therapy, have a left ventricular ejection fraction of < or = 35%, and a QRS width of > or = 120 ms. Improvement in symptoms or ventricular remodelling is observed in 50-80% of patients. In order to improve response to treatment, several strategies are proposed, including patient selection, lead positioning and device optimization.
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