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Updated: Jun 23, 2026

Cardiac Stress Test Induced by Dobutamine and Monitored by Cardiac Catheterization in Mice
Published on: February 10, 2013
Impressive ST-segment elevation during dobutamine stress echocardiography in a patient with normal coronary arteries:
Sofiene Rekik1, Falah Aboukhoudir, Stephane Andrieu
1Cardiology Department, Avignon Hospital Center, Avignon, France. sofienerek@yahoo.fr
Insights
ST-segment elevation during dobutamine stress echocardiography can occur without coronary artery disease, potentially due to dobutamine-induced coronary artery spasm. This case highlights a rare but serious complication during cardiac stress testing.
Area of Science:
- Cardiology
- Clinical Medicine
Background:
- Dobutamine stress echocardiography (DSE) is a common diagnostic tool.
- ST-segment elevation during DSE typically indicates severe coronary artery disease (CAD).
- Coronary artery spasm is a potential, though less common, cause of DSE-induced ST elevation.
Observation:
- A 56-year-old man with no prior cardiovascular history underwent DSE.
- The patient experienced intense precordial pain and significant 10-mm ST elevation during the procedure.
- Urgent cardiac catheterization was performed to investigate the cause.
Findings:
- Cardiac catheterization revealed no significant coronary artery stenoses.
- The findings suggest the ST elevation was not due to obstructive CAD.
- Coronary artery spasm induced by dobutamine is the suspected etiology.
Implications:
- This case underscores the importance of considering coronary artery spasm in DSE-induced ST elevation, even without obstructive CAD.
- It highlights a rare complication of dobutamine stress testing.
- Further investigation into the mechanisms of dobutamine-induced coronary artery spasm may be warranted.
Abstract:
ST-segment elevation during dobutamine stress echocardiography is a serious complication usually related to severe coronary artery disease. However, it can occur in absence of significant coronary artery disease supposedly as a consequence of an occlusive dobutamine-induced coronary artery spasm. We report the case of a 56-year-old man without cardiovascular history who presented during a dobutamine stress echocardiography an intense precordial pain along with an impressive 10-mm ST elevation and in whom urgent catheterization documented the absence of significant coronary artery stenoses.
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