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Specific binding of neoglycoproteins to Toxoplasma gondii tachyzoites
R Robert1, P L de la Jarrige, C Mahaza
1Laboratoire de Parasitologie, Faculté de Pharmacie, UFR de Sciences Médicales et Pharmaceutiques, Angers, France.
Infection and Immunity
|December 1, 1991
Abstract:
Several studies have shown that protozoa bind to glycoproteins or neoglycoproteins. Here we report that Toxoplasma gondii binds strongly to bovine serum albumin-glucosamide. The binding was rapid, time dependent, partially reversible, saturable, and specific. Scatchard analysis showed about 40,000 molecules of bovine serum albumin-glucosamide per toxoplasma cell. The apparent dissociation constant was found to be 4.46 x 10(-8) M.