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Related Experiment Video

Updated: Jun 23, 2026

Generation of Induced Pluripotent Stem Cells from Turner Syndrome (45XO) Fetal Cells for Downstream Modelling of Neurological Deficits Associated with the Syndrome
09:39

Generation of Induced Pluripotent Stem Cells from Turner Syndrome (45XO) Fetal Cells for Downstream Modelling of Neurological Deficits Associated with the Syndrome

Published on: December 4, 2021

Turner syndrome and anesthesia.

Marcius Vinícius M Maranhão1

  • 1Disciplina de Farmacologia do Instituto de Ciências Biológicas da Universidade de Pernambuco, Recife, PE. gabriel.n@uol.com.br

Revista Brasileira De Anestesiologia
|April 22, 2009
PubMed
Summary
This summary is machine-generated.

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Turner syndrome, a genetic disorder in women, presents significant airway and cardiovascular challenges for anesthesiologists. Understanding these anatomical changes ensures safer anesthetic management and reduces perioperative risks.

Area of Science:

  • Genetics
  • Anesthesiology
  • Medical Review

Background:

  • Turner syndrome is a genetic disorder (45X karyotype) causing gonadal dysgenesis and various anatomical/physiological changes.
  • Key concerns for anesthesiologists include difficult airways due to short neck and craniofacial hypoplasia.
  • Patients frequently have cardiac, endocrine, gastrointestinal, liver, kidney, and musculoskeletal issues requiring pre-anesthetic evaluation.

Purpose of the Study:

  • To review anatomopathologic changes in Turner syndrome relevant to anesthesiologists.
  • To discuss perioperative management strategies for these patients.
  • To review the literature on anesthetic conduct in Turner syndrome.

Main Methods:

  • Literature review of anatomopathologic changes and anesthetic management.

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  • Discussion of perioperative considerations for Turner syndrome patients.

    • Main Results:

    • Turner syndrome involves significant airway (short trachea, high bifurcation) and cardiovascular abnormalities.
    • Difficult airway management is a primary concern.
    • Anesthesia, both general and regional, appears safe with appropriate precautions.

    Conclusions:

    • Turner syndrome presents unique challenges for anesthesiologists due to associated anatomical abnormalities.
    • Knowledge of these specific patient characteristics is crucial for safe anesthetic administration.
    • Informed anesthetic management can lead to low perioperative morbidity and mortality.