Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Chronic Kidney Disease II: Clinical Manifestations01:24

Chronic Kidney Disease II: Clinical Manifestations

Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
Cushing Syndrome II: Pathophysiology01:19

Cushing Syndrome II: Pathophysiology

Cortisol production is normally governed by the hypothalamic–pituitary–adrenal (HPA) axis, which maintains hormonal balance through tightly regulated feedback mechanisms. Disruption of this regulatory system is central to the development of Cushing syndrome, whether the excess cortisol originates from external medications or internal pathology. Persistent cortisol elevation alters metabolism, immune function, and endocrine signaling, producing the characteristic clinical features of the...
Cushing Syndrome I: Introduction01:26

Cushing Syndrome I: Introduction

Cushing syndrome refers to the collection of clinical manifestations that arise when tissues are exposed to excessive amounts of cortisol or cortisol-like medications over an extended period. Cortisol, a glucocorticoid produced by the adrenal cortex, regulates metabolism, immune responses, and the body’s adaptation to stress. When its concentration remains chronically elevated, these physiological pathways become dysregulated, resulting in the characteristic features of the syndrome.Exogenous...
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
Nephrotic Syndrome II : Assessment and Medical Management01:26

Nephrotic Syndrome II : Assessment and Medical Management

IntroductionNephrotic syndrome is a kidney disorder marked by excessive protein loss in the urine, leading to various systemic complications. This condition often results from damage to the glomeruli—the kidney's filtering units—causing proteinuria, low blood protein levels, and fluid retention. Understanding the assessment, diagnosis, and management of nephrotic syndrome is essential for effective treatment and prevention of further kidney damage.AssessmentPatient History: Document any history...
Diabetic Ketoacidosis ll: Pathophysiology01:22

Diabetic Ketoacidosis ll: Pathophysiology

Diabetic ketoacidosis (DKA) is a metabolic emergency characterized by hyperglycemia, ketonemia, and metabolic acidosis. It results from severe insulin deficiency and an excess of counterregulatory hormones, leading to uncontrolled lipolysis, ketogenesis, and widespread electrolyte and fluid disturbances.Pathophysiology The central event in DKA is a profound loss of insulin action. Without insulin, glucose uptake in insulin-dependent tissues is impaired, while hepatic glucose production...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Allergic reaction to patent blue dye in breast surgery - case report.

Brazilian journal of anesthesiology (Elsevier)·2016
Same author

[Allergic reaction to patent blue dye in breast surgery - case report].

Revista brasileira de anestesiologia·2014
Same author

[Paralysis of the left vocal cord secondary to left recurrent nerve lesion following surgery for ligation of the arterial canal: case report.].

Revista brasileira de anestesiologia·2009
Same author

Anesthesia and cerebral palsy.

Revista brasileira de anestesiologia·2009
Same author

Turner syndrome and anesthesia.

Revista brasileira de anestesiologia·2009
Same author

[Guidelines for myocardial revascularization surgery].

Arquivos brasileiros de cardiologia·2004

Related Experiment Video

Updated: May 11, 2026

Iris Fixation via External Pentagram Suturing
05:22

Iris Fixation via External Pentagram Suturing

Published on: May 5, 2022

Kinsbourne syndrome: case report.

Marcius Vinícius M Maranhão1, Allana Cavalcanti Fulgino de Holanda, Felipe Lira Tavares

  • 1Institute of Biological Sciences, Universidade de Pernambuco, Brazil.

Brazilian Journal of Anesthesiology (Elsevier)
|May 21, 2013
PubMed
Summary
This summary is machine-generated.

Kinsbourne syndrome, a rare childhood neurological disorder, can be associated with mediastinal tumors. Surgical tumor resection and careful anesthetic drug selection are crucial for successful outcomes in affected children.

Related Experiment Videos

Last Updated: May 11, 2026

Iris Fixation via External Pentagram Suturing
05:22

Iris Fixation via External Pentagram Suturing

Published on: May 5, 2022

Area of Science:

  • Pediatric Neurology
  • Pediatric Oncology
  • Anesthesiology

Background:

  • Kinsbourne syndrome is a rare neurological disorder affecting children aged 6-36 months.
  • Characterized by opsoclonus, myoclonus, and cerebellar ataxia.
  • Often associated with neuroblastomas, hepatoblastomas, and ganglioneuromas, suggesting a paraneoplastic etiology.

Observation:

  • A case report details a 1-year, 5-month-old child diagnosed with Kinsbourne syndrome and a posterior mediastinal tumor.
  • The child underwent surgical resection of the mediastinal tumor.
  • Anatomopathological examination confirmed the tumor as a ganglioneuroblastoma.

Findings:

  • Anesthesia was induced and maintained using sevoflurane, nitrous oxide, fentanyl, and rocuronium.
  • Neuromuscular block reversal was achieved with neostigmine and atropine.
  • Postoperative analgesia included dipyrone, morphine, and ketoprofen, with no complications reported.

Implications:

  • The anesthetic management proved safe and facilitated an uneventful procedure.
  • Certain anesthetic agents, like ketamine and etomidate, should be avoided as they may exacerbate Kinsbourne syndrome symptoms.
  • This case highlights the importance of multidisciplinary care in managing pediatric paraneoplastic syndromes.