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Related Concept Videos

Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
Imaging Studies IV: Magnetic Resonance Imaging01:27

Imaging Studies IV: Magnetic Resonance Imaging

Introduction:Magnetic Resonance Imaging, or MRI, can include a specialized imaging technique of the urinary system known as Magnetic Resonance Urography (MRU). This radiation-free technique uses strong magnetic fields and radio waves to produce detailed images with the help of a computer. MRU is particularly effective for visualizing fluid-filled structures like the kidneys, ureters, and bladder.Applications of MRI in the Genitourinary SystemKidneys and Ureters: MRI detects tumors, cysts,...

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Related Experiment Video

Updated: Jun 23, 2026

Probe-based Confocal Laser Endomicroscopy of the Urinary Tract: The Technique
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Probe-based Confocal Laser Endomicroscopy of the Urinary Tract: The Technique

Published on: January 10, 2013

MRI endoscopy using intrinsically localized probes.

Shashank Sathyanarayana1, Paul A Bottomley

  • 1Department of Radiology, Division of MR Research, Johns Hopkins University, Baltimore, Maryland 21287, USA.

Medical Physics
|April 22, 2009
PubMed
Summary
This summary is machine-generated.

This study introduces an "MRI endoscope" using internal probes for high-resolution imaging, moving beyond traditional fixed MRI systems. This novel approach enhances localized imaging capabilities within the device

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Area of Science:

  • Medical Imaging
  • Biomedical Engineering
  • Physics

Background:

  • Traditional Magnetic Resonance Imaging (MRI) is confined to the laboratory frame of reference.
  • Existing MRI methods lack the ability to image within the device's own frame of reference.

Purpose of the Study:

  • To develop and demonstrate a high-resolution MRI method using active, catheter-based internal probes.
  • To transform MRI from the laboratory frame of reference to the device's frame of reference, enabling endoscopic imaging.

Main Methods:

  • Utilized tiny, catheter-based internal probes for localization, leveraging intrinsic spatial properties.
  • Employed loop coils and loopless antennas with modified sensitivity and adiabatic excitation.
  • Restricted MRI sensitivity to a thin, disk-shaped plane (a few mm thick).
  • Demonstrated the method at 3 Tesla (3 T).

Main Results:

  • Achieved high-resolution imaging with in-plane resolution as small as 80 micrometers and slice thickness of 1.5-5 mm.
  • Localized MRI sensitivity to a thin plane, significantly reducing eddy currents.
  • Ensured safety with maximum local temperature increases below 1°C, adhering to regulatory guidelines.
  • Successfully demonstrated the technique in various biological samples, including a kiwifruit, aortas, and a human iliac artery specimen.

Conclusions:

  • The developed
  • MRI endoscope
  • offers a novel approach for high-resolution, localized imaging.
  • This method overcomes the limitations of traditional MRI by operating within the device's frame of reference.
  • The technology shows promise for advanced diagnostic and interventional procedures in various medical fields.