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Updated: Jun 23, 2026

Use of a Linear Accelerator for Conducting In Vitro Radiobiology Experiments
Published on: May 26, 2019
Clinic based transfer of the N(D,W)(60Co) calibration coefficient using a linear accelerator
W Abdel-Rahman1, M D C Evans, L Serré
1Department of Medical Physics, McGill University Health Centre, 1650 Avenue Cedar Montreal, Quebec H3G 1A4, Canada. wabdel@medphys.mcgill.ca
Abstract:
Ionization chambers used for reference dosimetry require a local secondary standard ionization chamber with a 60Co absorbed dose to water calibration coefficient N(D,W)(60Co) traceable to a national primary standards dosimetry laboratory or an accredited secondary dosimetry calibration laboratory. Clinic based (in-house) transfer of this coefficient to tertiary reference ionization chambers has traditionally been accomplished with chamber cross calibration in water using a 60Co beam; however, access to 60Co teletherapy machines has become increasingly limited for clinic based physicists. In this work, the accuracy of alternative methods of transferring the N(D,W)(60Co) calibration coefficient using 6 and 18 MV photon beams from a linear accelerator in lieu of 60Co has been investigated for five different setups and four commonly used chamber types.
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