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Updated: Jun 23, 2026

Pulse Wave Velocity Testing in the Baltimore Longitudinal Study of Aging
Published on: February 7, 2014
An evaluation of the cuffless blood pressure estimation based on pulse transit time technique: a half year study on
Mico Yee-Man Wong1, Carmen Chung-Yan Poon, Yuan-Ting Zhang
1Joint Research Centre for Biomedical Engineering, Department of Electronic Engineering, The Chinese University of Hong Kong, Shatin, Hong Kong.
Abstract:
In the present study, we investigated the relationship between blood pressure (BP) and pulse transit time (PTT) and evaluated the accuracy of the PTT-based cuffless BP estimation on 14 normotensive subjects. Least-squares regression was used to estimate BP in the first test and a repeatability test carried out half year later. BP in the repeatability test was also estimated using the regression coefficients in the first test. The results illustrated that in the first and repeatability tests (1) arterial BP increased and PTT decreased acutely after the exercises and (2) systolic BP was highly correlated with PTT. In the repeatability test, the estimation differences from the references were 0.0 +/- 5.3 mmHg and 0.0 +/- 2.9 mmHg for systolic and diastolic BPs respectively using least-squares regression. However, the estimation differences increased to 1.4 +/- 10.2 mmHg and 2.1 +/- 7.3 mmHg for systolic and diastolic BPs, respectively when the regression coefficients in the first test were used for prediction. In summary, reasonable BP estimations were given in the first and repeatability tests but not using the regression coefficients obtained 6 months ago for some subjects.
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This invasive approach involves cannulating a peripheral artery. During each cardiac contraction, pressure generates mechanical motion within the catheter, transmitted through rigid, fluid-filled tubing to a transducer. This transducer converts mechanical motion into electrical signals displayed as waveforms on a monitor. An automatic flushing system prevents blood backflow. Due to the potential risk of unexpected arterial blood loss, this method is primarily used in intensive...
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