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Updated: Jun 23, 2026
10:27
Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
Published on: December 15, 2011
Two cases of pyodermatitis-pyostomatitis vegetans.
Hyun-Chang Ko1, Do-Sang Jung, Seung-Wook Jwa
1Department of Dermatology, School of Medicine, Pusan National University, Busan 602-739, Korea.
The Journal of Dermatology
|April 23, 2009
Summary
Pyodermatitis-pyostomatitis vegetans (PPV) is a rare skin condition. This study presents cases of PPV without associated inflammatory bowel disease, challenging its role as a sole indicator.
Area of Science:
- Dermatology
- Gastroenterology
Background:
- Pyodermatitis-pyostomatitis vegetans (PPV) is a rare chronic mucocutaneous dermatosis characterized by pustular and vegetating lesions.
- Oral lesions manifest as friable, yellowish pustules forming "snail tracts," while cutaneous lesions present as coalescing papulopustules forming vegetating plaques.
Observation:
- PPV is often considered a marker for inflammatory bowel disease (IBD), with approximately 70% of reported cases showing concurrence.
- This report details two patients with typical clinical and histopathological features of PPV.
Findings:
- Neither patient presented with concurrent inflammatory bowel disease.
- These findings suggest PPV may occur independently of IBD.
Implications:
- The association between PPV and IBD may not be as absolute as previously thought.
- Further research is needed to understand the etiological factors of PPV and its relationship with gastrointestinal disorders.
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