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Related Concept Videos

Bone Remodeling01:40

Bone Remodeling

Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
The Bone Matrix01:18

The Bone Matrix

Bone contains a relatively small number of cells entrenched in a matrix of collagen fibers that provide an adherent surface for inorganic salt crystals. Both components of the matrix, organic and inorganic, contribute to the unusual properties of bone. Without collagen, bones would be brittle and shatter easily. Without mineral crystals, bones would flex and provide little support. This can be observed by an experiment: when the minerals of a bone are dissolved by soaking the bone in acid or...
Bone Remodeling and Repair01:31

Bone Remodeling and Repair

Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during bone...
Bone Structure01:55

Bone Structure

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Bone Cells and Tissue01:30

Bone Cells and Tissue

Bones contain a relatively small number of cells entrenched in a matrix of organic and inorganic components. Although bone cells compose only a small amount of the bone volume, they are crucial to its function. Four types of cells are found within the bone tissue— osteoblasts, osteocytes, osteogenic cells, and osteoclasts.
Osteoblasts and Osteocytes
The osteoblast is the bone cell responsible for forming new bone tissue. It is found in the growing portions of bone, including the periosteum and...
Bone as Supporting Connective Tissue01:23

Bone as Supporting Connective Tissue

Bone tissue forms the internal skeleton of vertebrate animals, providing structure to the body.
Bone Matrix
Bone, or osseous tissue, is a connective tissue that has a large amount of two different types of matrix material. The organic matrix is similar to the matrix material found in other connective tissues, including some amount of collagen and elastic fibers. This gives strength and flexibility to the tissue. The inorganic matrix consists of mineral salts— mostly calcium salts— that give the...

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Updated: Jun 23, 2026

Subject-specific Musculoskeletal Model for Studying Bone Strain During Dynamic Motion
09:32

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Published on: April 11, 2018

Studies on constitutive equation that models bone tissue.

Marek Pawlikowski1, Marian Klasztorny, Konstanty Skalski

  • 1Institute of Mechanics and Printing, Warsaw University of Technology, Warszawa, Poland. mpawlik1@wip.pw.edu.pl

Acta of Bioengineering and Biomechanics
|April 24, 2009
PubMed
Summary

A new method models bone's viscoelastic properties, considering anisotropy and non-homogeneity. This approach uses creep tests to determine elastic and viscoelastic constants for accurate bone rheological analysis.

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Area of Science:

  • Biomechanics
  • Materials Science
  • Orthopedics

Background:

  • Bone exhibits complex viscoelastic behavior crucial for understanding its mechanical function.
  • Existing models often simplify bone's anisotropic and non-homogeneous nature.
  • Accurate characterization of bone's viscoelasticity is essential for advanced structural analysis and medical applications.

Purpose of the Study:

  • To develop a method for identifying viscoelastic constitutive equations for bone.
  • To incorporate anisotropy, non-homogeneity, and bone remodeling into rheological models.
  • To establish a robust algorithm for determining bone's elastic and viscoelastic material parameters.

Main Methods:

  • Developed a method based on a monotropic rheological model for bone.
  • Utilized creep compression and shear tests on calf femur samples.
  • Employed fractional exponential and normal exponential functions to describe rheological processes.
  • Formulated constitutive equations in compliance form.

Main Results:

  • Successfully determined five elastic and viscoelastic constants for a monotropic bone material.
  • Developed and utilized a computer program to execute the material constant determination algorithm.
  • Demonstrated a method for calculating critical material constants for strain and stress analysis.

Conclusions:

  • The proposed method accurately identifies viscoelastic constitutive equations for bone.
  • The approach accounts for key bone characteristics like anisotropy and non-homogeneity.
  • This work provides a valuable tool for rheological modeling and mechanical analysis of bone tissue.