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Updated: Jun 23, 2026
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A New Straightforward Method for Lipophilicity (logP) Measurement using 19F NMR Spectroscopy
Published on: January 30, 2019
Fluorinated carbohydrates as lectin ligands: versatile sensors in 19F-detected saturation transfer difference NMR
Tammo Diercks1, João P Ribeiro, F Javier Cañada
1NMR facility, CiC bioGUNE, Parque Tecnológico de Bizkaia, Ed. 800, 48160 Derio, Spain.
Chemistry (Weinheim an Der Bergstrasse, Germany)
|April 24, 2009
Abstract:
As a novel approach for studying carbohydrate-lectin interactions spectroscopically, we combine the resolution and specificity of (19)F-detected NMR spectroscopy with the sensitivity of the saturation transfer difference (STD) technique. The resulting background-free (19)F-STD spectra open a promising perspective for broad application with medical relevance, for example, in drug discovery.
