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Long-term physical outcome in patients with septic shock
J B Poulsen1, K Møller, H Kehlet
1Department of intensive Care, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark. jesper.poulsen@rh.regionh.dk
Acta Anaesthesiologica Scandinavica
|April 25, 2009
Summary
Septic shock survivors experience significantly impaired physical function one year post-discharge, with reduced scores and a doubled need for assistance. This highlights long-term physical deficits in sepsis survivors.
Area of Science:
- Intensive Care Medicine
- Critical Care Medicine
- Rehabilitation Medicine
Background:
- Limited data exists on long-term physical function following septic shock.
- Septic shock survivors often face significant health challenges post-discharge.
Purpose of the Study:
- To evaluate the physical function of septic shock survivors one year after hospital discharge.
- To identify factors influencing physical recovery in this patient population.
Main Methods:
- A cohort of 174 adult patients with septic shock was studied.
- Survivors (70) were assessed using the Short Form-36 survey and interviewed about socioeconomic status.
- Pre-ICU Functional Comorbidity Index (FCI) was recorded.
Main Results:
- Survivors showed markedly reduced physical component summary scores (PCS) compared to controls (36 vs. 47, P<0.0001).
- Reduced PCS persisted even in patients without pre-existing comorbidities.
- Loss of muscle mass was cited as the primary cause of decreased function by 81% of patients.
Conclusions:
- Physical function is substantially compromised in septic shock survivors one year after discharge.
- Pre-ICU comorbidities negatively correlate with long-term physical function.
- Return to work decreased, and need for home assistance doubled.
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