Related Experiment Video
Updated: Jun 23, 2026
A Step by Step Protocol for Subretinal Surgery in Rabbits
Published on: September 13, 2016
Comparison of 25, 23 and 20-gauge vitrectomy
1Mid Atlantic Retina, Thomas Jefferson University, Wills Eye Institute, Philadelphia, Pennsylvania 19106, USA. spirnm01@yahoo.com
Purpose Of Review:
The history and development of 25-gauge and 23-gauge vitrectomy are reviewed in this paper and compared with 20-gauge vitrectomy, the historical gold standard. Current advantages and disadvantages of each are delineated.
Recent Findings:
Transconjunctival sutureless vitrectomy continues to offer advantages of increased patient comfort decreased operative times and improved postoperative astigmatism. These advantages, however, must be weighed against the possibility of increased rates of postoperative hypotony and endopthalmitis.
Summary:
Both 25-gauge and 23-gauge instruments continue to evolve, and have improved significantly since their introductions. Most cases can now be performed using either 25-gauge or 23-gauge techniques with success rates comparable to 20-gauge. Despite these advantages, there are still cases where 20-gauge is appropriate and preferable. Clinical experience, innovations and further studies will help dictate the future course of pars plana vitrectomy instrumentation.
