Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Toxoplasmosis01:28

Toxoplasmosis

Toxoplasmosis, a zoonotic disease caused by the protozoan Toxoplasma gondii, poses significant public health challenges globally due to its high seroprevalence and varied clinical manifestations. As an obligate intracellular parasite, T. gondii can infect all warm-blooded vertebrates, but felids are its only definitive hosts, shedding unsporulated oocysts into the environment. Humans typically acquire the infection through ingestion of tissue cysts in undercooked meat or oocysts from...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Subtypes of <i>Blastocystis</i> sp. isolated in fecal samples from transplant candidates in São Paulo, Brazil.

Parasite epidemiology and control·2019
Same author

Screening of Strongyloides infection using an ELISA test in transplant candidates.

Clinics (Sao Paulo, Brazil)·2019
Same author

Molecular diagnosis of Strongyloides stercoralis among transplant candidates.

Transplant infectious disease : an official journal of the Transplantation Society·2018
Same author

Involvement of dopaminergic and cholinergic pathways in the induction of yawning and genital grooming by the aqueous extract of Saccharum officinarum L. (sugarcane) in rats.

Neuroscience letters·2014
Same author

Influenza B outbreak on a cruise ship off the São Paulo Coast, Brazil.

Journal of travel medicine·2014
Same author

IgG antibody responses in mice coinfected with Toxocara canis and other helminths or protozoan parasites.

Revista do Instituto de Medicina Tropical de Sao Paulo·2012

Related Experiment Video

Updated: Jun 23, 2026

Experimental Infection of Mice with the Parasitic Nematode Strongyloides ratti
10:12

Experimental Infection of Mice with the Parasitic Nematode Strongyloides ratti

Published on: January 17, 2025

Muscular strength decrease in Rattus norvegicus experimentally infected by Toxocara canis.

Pedro P Chieffi1, Renata T R Aquino, Maria A Paschoalotti

  • 1Faculdade de Ciências Médicas da Santa Casa de São Paulo, São Paulo, SP, Brasil. pchieffi@usp.br

Revista Do Instituto De Medicina Tropical De Sao Paulo
|April 25, 2009
PubMed
Summary

Toxocara canis infection in rats impairs muscular strength, particularly in the forelimbs, 30 days post-inoculation. Body weight remained unaffected in infected versus control groups.

More Related Videos

Versatility of Protocols for Resistance Training and Assessment Using Static and Dynamic Ladders in Animal Models
08:31

Versatility of Protocols for Resistance Training and Assessment Using Static and Dynamic Ladders in Animal Models

Published on: December 17, 2021

Measuring the Strength of Mice
06:17

Measuring the Strength of Mice

Published on: June 2, 2013

Related Experiment Videos

Last Updated: Jun 23, 2026

Experimental Infection of Mice with the Parasitic Nematode Strongyloides ratti
10:12

Experimental Infection of Mice with the Parasitic Nematode Strongyloides ratti

Published on: January 17, 2025

Versatility of Protocols for Resistance Training and Assessment Using Static and Dynamic Ladders in Animal Models
08:31

Versatility of Protocols for Resistance Training and Assessment Using Static and Dynamic Ladders in Animal Models

Published on: December 17, 2021

Measuring the Strength of Mice
06:17

Measuring the Strength of Mice

Published on: June 2, 2013

Area of Science:

  • Parasitology
  • Animal models in research
  • Neuromuscular studies

Background:

  • Toxocara canis is a nematode parasite that can infect various animal hosts, including rodents.
  • Larval migration through tissues may potentially impact host physiology and behavior.
  • Understanding the effects of parasitic infections on host muscular function is crucial for public health and veterinary medicine.

Purpose of the Study:

  • To investigate the impact of Toxocara canis larval infection on the muscular strength of Rattus norvegicus.
  • To determine if different infection doses affect the severity of muscular impairment.
  • To assess changes in body weight as an indicator of overall health status.

Main Methods:

  • Fifty Wistar rats were divided into three groups: two infected with different doses of Toxocara canis eggs (300 or 2,000) and one control group.
  • Muscular strength in the fore-feet was measured at 10 and 30 days post-infection.
  • Body weight was recorded concurrently with muscular strength assessments.

Main Results:

  • No significant differences in body weight were observed between infected and control rats at any time point.
  • A notable impairment in forelimb muscular strength was detected in rats infected with Toxocara canis 30 days after inoculation.
  • The severity of muscular impairment was not explicitly detailed in relation to the different infection doses.

Conclusions:

  • Toxocara canis infection can lead to a reduction in muscular strength in Rattus norvegicus.
  • The observed muscular impairment occurs approximately 30 days post-infection.
  • Parasitic infections can have sub-clinical effects on host motor function without significantly altering body weight.