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Related Concept Videos

Mitral Stenosis III: Medical Management01:26

Mitral Stenosis III: Medical Management

Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
Mitral Valve Prolapse I: Introduction01:27

Mitral Valve Prolapse I: Introduction

IntroductionThe mitral valve, one of the heart's four valves, regulates blood flow. These valves have flaps that open and close to direct blood properly through the heart and body. During each heartbeat, the flaps open for blood to pass through and seal shut to prevent backflow. Specifically, the mitral valve opens to allow blood flow from the heart's upper left chamber to the lower left chamber. It then closes securely as the lower left chamber contracts to pump blood to the body, preventing...
Mitral Regurgitation III: Medical Management01:25

Mitral Regurgitation III: Medical Management

Mitral regurgitation (MR) is characterized by retrograde blood circulation from the left ventricle into the left atrium due to inadequate mitral valve closure. The severity of the condition, symptoms, and underlying cause determine treatment strategies.Monitoring and Pharmacological TreatmentPatients with mild to moderate MR typically do not need immediate intervention but regular monitoring to assess progression and guide treatment. Patients with mild MR should have an echocardiogram every 3-5...
Mitral Valve Prolapse II: Assessment and Management01:22

Mitral Valve Prolapse II: Assessment and Management

IntroductionA range of clinical features characterizes Mitral Valve Prolapse (MVP), but it is important to note that many individuals with MVP are asymptomatic and may remain so throughout their lives. For those who do exhibit symptoms, the following are the key clinical features:Palpitations: This is a common symptom where individuals feel an irregular or rapid heartbeat. Palpitations in MVP are often due to arrhythmias such as premature ventricular contractions or supraventricular tachycardia.
Mitral Valve Prolapse III: Nursing Management01:19

Mitral Valve Prolapse III: Nursing Management

The nursing management of Mitral Valve Prolapse, or MVP, centers around patient education, symptom monitoring, and lifestyle modifications.Patient Education on MVP Diagnosis and Heredity: Nurses should provide comprehensive education about MVP, a condition where the mitral valve does not close appropriately during heartbeats. This education often includes the condition's pathophysiology, symptoms, and potential complications, like arrhythmias or mitral regurgitation. Though not fully...
Mitral Regurgitation I: Introduction01:20

Mitral Regurgitation I: Introduction

Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...

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Related Experiment Video

Updated: Jun 23, 2026

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
08:31

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair

Published on: October 16, 2021

Off-pump transapical mitral valve replacement.

Georg Lutter1, René Quaden, Satoru Osaki

  • 1Department of Cardiovascular Surgery, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany. lutter@kielheart.uni-kiel.de

European Journal of Cardio-Thoracic Surgery : Official Journal of the European Association for Cardio-Thoracic Surgery
|April 28, 2009
PubMed
Summary
This summary is machine-generated.

This study shows that a self-expanding valved stent can be implanted in the mitral position in pigs, demonstrating feasibility for minimally invasive mitral valve replacement. Further research is needed for long-term outcomes.

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Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
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Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
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Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement

Published on: December 11, 2017

Area of Science:

  • Cardiovascular Surgery
  • Biomedical Engineering
  • Interventional Cardiology

Background:

  • Percutaneous valve replacement is a developing technique, currently limited to aortic and pulmonary valves in select patients.
  • Minimally invasive mitral valve replacement requires innovative device development and delivery systems.

Purpose of the Study:

  • To evaluate a novel self-expanding valved stent for minimally invasive mitral valve replacement in an animal model.
  • To assess the feasibility and acute performance of transcatheter mitral valve implantation.

Main Methods:

  • A new nitinol stent with bovine pericardial valve and atrial anchoring springs was designed.
  • Seven pigs underwent off-pump mitral valved stent implantation via a transapical approach under transoesophageal echocardiographic guidance.
  • The delivery system was designed for minimally invasive access through a mini-sternotomy.

Main Results:

  • The valved stent demonstrated precise deployment and accurate positioning, minimizing paravalvular leakage.
  • Successful implantation was achieved in 6 out of 7 animals, with minimal to mild mitral regurgitation.
  • Surviving animals remained hemodynamically stable for one hour post-procedure.

Conclusions:

  • Transcatheter implantation of a bovine pericardial valved stent in the mitral position is feasible in pigs.
  • The delivery system utilized was smaller than previously reported mitral valve stent systems.
  • Long-term feasibility, durability, and functional impact require further investigation.