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Updated: Jun 23, 2026

Computed Tomography-guided Time-domain Diffuse Fluorescence Tomography in Small Animals for Localization of Cancer Biomarkers
Published on: July 17, 2012
Algorithms for 3D localization and imaging using near-field diffraction tomography with diffuse light
Abstract:
We introduce two filtering methods for near-field diffuse light diffraction tomography based on the angular spectrum representation. We then combine these filtering techniques with a new method to find the approximate depth of the image heterogeneities. Taken together these ideas improve the fidelity of our projection image reconstructions, provide an interesting three dimensional rendering of the reconstructed volume, and enable us to identify and classify image artifacts that need to be controlled better for tissue applications. The analysis is accomplished using data derived from numerical finite difference simulations with added noise.
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